Testosterone Replacement Therapy (TRT) Decreases Ferritin

[Nelson Vergel]

Testosterone replacement can cause a decrease in ferritin in men even without the presence or use of blood donations or therapeutic phlebotomies. A study gave men testosterone enanthate at a dose of 125 mg per week (it also used T enanthate with or without finasteride to see the effect of blocking 5 alpha reductase while on TRT). These are the ferritin values after 3 months. Ferritin was reduced at an average of 32% within 3 months of treatment initiation without altering iron, transferrin, or transferrin saturation.

Source: Testosterone alters iron metabolism and stimulates red blood cell production independently of dihydrotestosterone

Ferritin

Ferritin is a protein that stores iron. Red blood cells need iron to form normally and carry oxygen around your body. Low levels of ferritin lead to iron deficiency anemia, which means you have too few red blood cells. High levels of ferritin can damage your joints, heart, liver, and pancreas.

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[Nelson Vergel]

Higher Testosterone was Associated with Lower Ferritin

Higher Testosterone was Associated with Lower Ferritin The Association between the Levels of Serum Ferritin and Sex Hormones in a Large Scale of Chinese Male Population Liu, Zhenfang ; Ye, Fanghui ; Zhang, Haiying ; Gao, Yong ; Tan, Aihua ; Zhang, Shijun ; Xiao, Qiang ; Zhang, Bing ; Huang...

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[Nelson Vergel]

Warning for Men on TRT: Low Ferritin is Bad

Thanks everyone and being very new to TRT I learned a lot from you guys. Taked to Dr Saya and I am so greatful that he got me in quickly. I am overseas and had to stay up like past midnight to talk to him but it was worth it. He put me on 4 weeks of 200 iu HCG per day to jump start my system...

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[Nelson Vergel]

Iron Deficiency (Low Ferritin) without Anemia

I found an interesting read on iron deficiency without anemia (which is what most of us frequent blood donors have). They even mention TRT as a cause: Iron Deficiency Without Anemia – Common, Important, Neglected

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TRT, Low Ferritin, Possible Iron Deficiency Anemia

Been on TRT for 5 years. (Age 48 years). Never had hemoglobin or hematocrit get outside of range, but would occasionally get close to upper limit at times. Started donating blood on an occasional basis (2-3 times per year) with no issues. Starting in January 2016, I thought I would be a good...

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Need to build my Ferritin Back up. Need suggestions please.

In the effort to keep my HCT under 50.1 I have needed to donate blood. Because of that I have pretty much crashed my Ferritin. I am looking for ideas on diet and supplements to get my blood built back up asap.

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[JimGainz]

This is interesting. I would assume those of who frequently give blood on TRT to manage hematocrit are particularly vulnerable to low ferritin.

 

[andrewBwinter]

Testosterone replacement can cause a decrease in ferritin in men even without the presence or use of blood donations or therapeutic phlebotomies. A study gave men testosterone enanthate at a dose of 125 mg per week (it also used T enanthate with or without finasteride to see the effect of blocking 5 alpha reductase while on TRT). These are the ferritin values after 3 months. Ferritin was reduced at an average of 32% within 3 months of treatment initiation without altering iron, transferrin, or transferrin saturation.

View attachment 14566
Source: Testosterone alters iron metabolism and stimulates red blood cell production independently of dihydrotestosterone

Ferritin

Ferritin is a protein that stores iron. Red blood cells need iron to form normally and carry oxygen around your body. Low levels of ferritin lead to iron deficiency anemia, which means you have too few red blood cells. High levels of ferritin can damage your joints, heart, liver, and pancreas.

www.discountedlabs.com

Had to like this because I'm at 120 mg Test-E per week.