SHBG, EGFR, and Hypothyroidism...

[jth0524]

SHBG is talked about a lot as a good predictor of how fast one clears testosterone out of their body. Low SHBG frequently necessitates the need for more frequent injections per week. Do factors such as EGFR and hypothyroidism also factor into how fast an individual processes testosterone? On the surface, it would appear to make sense that EGFR and thyroid health could possibly also be factors in the speed at which one processes through testosterone. Thanks in advance for any feedback.

 

[Systemlord]

Thyroid hormones speeds up every cell in the body, if your thyroid hormones are less than optimal, so to will your results on TRT. You will be unable to dial in a TRT protocol if thyroid hormones are low as you place high demands on a sluggish thyroid, as you improve upon a TRT protocol, thyroid goes in the opposite direction since demands are higher.