Progesterone and fertility in males

[Gman86]

Does anyone know whether exogenous progesterone increases or decreases fertility in males?

 

[Nelson Vergel]

Good question. I have not seen any data.

It may increase 17-OH-progesterone, which has been linked to increased intratesticular testosterone and sperm. But I am not sure if there is a threshold.

Best hCG Dose with TRT: 17-Hydroxyprogesterone Lab Test

The use of testosterone replacement therapy (TRT) increases blood levels of testosterone but, surprisingly, it decreases the level of testosterone inside the testicles (Intratesticular testosterone or ITT). ITT is key for proper sperm production. This ITT decrease is due to the LH and FSH shut...

www.excelmale.com

 

[Gman86]

Good question. I have not seen any data.

It may increase 17-OH-progesterone, which has been linked to increased intratesticular testosterone and sperm. But I am not sure if there is a threshold.

View attachment 19216

Best hCG Dose with TRT: 17-Hydroxyprogesterone Lab Test

The use of testosterone replacement therapy (TRT) increases blood levels of testosterone but, surprisingly, it decreases the level of testosterone inside the testicles (Intratesticular testosterone or ITT). ITT is key for proper sperm production. This ITT decrease is due to the LH and FSH shut...

www.excelmale.com

Since I posted that I’m thinking that progesterone, if kept within or close to the normal male range, is a promoter of fertility. The name itself literally means “pro-gestation” but that’s referring to women, so not 100% sure if it’s as promoting of fertility in males. However, I did watch something where the woman explained that progesterone is needed for sperm to form their tails, which is obv important for it to be able to get its way into the egg. So overall I’m still unsure whether it’s fertility promoting or inhibiting, in males, but I’m currently leaning towards it being fertility promoting. Again, as long as ur not taking too much and ur prog levels fall within, or slightly above the normal male range. I’ve heard that there’s guys using very high dosages of prog on ray peats forum and it was apparently fertility inhibiting at those high levels