Post menopausal women on hormone therapy had lower risk of death due to COVID-19

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Nelson Vergel

This study investigates how using additional (exogenous) estrogen, like in menopausal hormone therapy (MHT) or birth control pills, impacts the risk of death from COVID-19 in women.

After analyzing data from several studies, the researchers found that postmenopausal women using MHT were less likely to die from COVID-19 compared to those who did not use MHT. The odds of death for these women were about 72% lower (with an odds ratio of 0.28).

However, for premenopausal women taking birth control pills, there was no significant difference in their odds of dying from COVID-19 compared to women not taking the pill.

The study also found that postmenopausal women using MHT were slightly more likely to be hospitalized or admitted to the ICU due to COVID-19, but there wasn't a significant difference in their need for respiratory support.

This research helps inform postmenopausal women that if they're using MHT and catch COVID-19, they have a lower risk of death than women who aren't using MHT. However, the researchers caution that the types and amounts of estrogen used varied between studies, which could impact the results. Also, all the studies included were cohort studies, which means they observed groups of people over time and did not conduct interventions, limiting the strength of their conclusions.

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