Help me create a Hydrocortisone treatment

Vvs1

Active Member
Hey guys, quick background, I have high reverse t3, low salivary cortisol, and high shbg.

I have tried t3 meds that really didn’t do much besides increase shbg , and I’m now on Natesto only

I want to try hydrocortisone, Hisone, from ADC. Articles I have read on low cortisol claim my cortisol is in a range that is beyond self repair, and requires HC. Plus all of these vitamin C/adrenal cocktail drinks are actually counterproductive for low cortisol.

I’d want to to a protocol to recover my natural adrenal function, and not rely on Hydrocortisone.

Theres 5 and 20 mg tablets of Hydrocortisone available. May add bioidentical progesterone cream on the back of my neck for a neurosteroid bump, if that’s even possible.
 

wondering

Active Member
Start w/ 10mg upon waking (keep on your nightstand). You should never take more than 10mg at one time.

See if that helps you. If not, you can add 5mg more at lunch time (approx. 5 hours later).

See if that helps. If not, you can add 2.5mg or 5mg 5 hours later.

I wouldn't go higher than 20 or 25mg. Again, never more than 10mg at a time and that should be reserved for first thing in AM.

You will not be fixed over night, it takes time for your HPA to recover. Months if not year or so. If you add afternoon or evening doses, after a few months, you can slowly back off the evening dose and then the lunchtime dose. If taking 5mg, cut to 2.5mg and so on.

The 10mg morning dose should be last to drop - I still haven't given it up.
 
Last edited:

Vvs1

Active Member
Start w/ 10mg upon waking (keep on your nightstand). You should never take more than 10mg at one time.

See if that helps you. If not, you can add 5mg more at lunch time (approx. 5 hours later).

See if that helps. If not, you can add 2.5mg or 5mg 5 hours later.

I wouldn't go higher than 20 or 25mg. Again, never more than 10mg at a time and that should be reserved for first thing in AM.

You will not be fixed over night, it takes time for your HPA to recover. Months if not year or so. If you add afternoon or evening doses, after a few months, you can slowly back off the evening dose and then the lunchtime dose. If taking 5mg, cut to 2.5mg and so on.

The 10mg morning dose should be last to drop - I still haven't given it up.

Is it ok to take a morning dose inconsistently? I don’t want to develop a tolerance or my own adrenals shutting down from outside hormones?

I always feel terrible when I take a cortisol reducer/blocker such as chamomile tea.
 

wondering

Active Member
Is it ok to take a morning dose inconsistently? I don’t want to develop a tolerance or my own adrenals shutting down from outside hormones?

I always feel terrible when I take a cortisol reducer/blocker such as chamomile tea.

If you dose properly as described you are NOT shutting your system down you are supplementing. You can always stress dose when sick or under extreme stress, but I would take the 10mg every day if needed or you will always just be coping and never get better. Just my two cents.
 

Vvs1

Active Member
If you dose properly as described you are NOT shutting your system down you are supplementing. You can always stress dose when sick or under extreme stress, but I would take the 10mg every day if needed or you will always just be coping and never get better. Just my two cents.

Thanks for the help. I have low morning cortisol and a huge drop midday.

What improvements or unfavorable changes have you noticed from HC? Do you add T3? I’m high in reverse t3.
 

wondering

Active Member
Thanks for the help. I have low morning cortisol and a huge drop midday.

What improvements or unfavorable changes have you noticed from HC? Do you add T3? I’m high in reverse t3.

At my worst, I couldn't leave the house or sleep - the anxiety was unbearable. Blood sugar was always low. Light headed. Depressed. Horrible.

HC helped me cope and slowly I got better. Winter is especially hard. The longer days will help you as Spring arrives. HC saved me, it really did.
 

wondering

Active Member
Have you found your ability to tolerate thyroid increase with adrenal support via HC supplementation? When you tried T3 in the past, what happened? Anxiety, palpitations, nervousness etc?

Yes, once my HPA seemed to settle down, Thyroid became much easier to tolerate. Dr. Mariano used to say.. the perfect test of HPA status is taking Thyroid hormone.

T3 alone just made my heart beat too fast and felt too ramped up. I convert T4 to T3 pretty well. So, I actually need a touch of Levothyroxine along with my daily NP Thyroid to get the right balance.
 
Do you think Adrenal Cortex Extract could achieve the same or similar? Interesting you mention Dr. Mariano, i see him mentioned everywhere yet I can't find any content from him directly online. Does he have any resources you could point me towards?

I already know the same would happen to me if I tired T3 - even low dose caffeine gives me the same things you mentioned.

Thanks for sharing your experience.
 

Jurek Kletsy

New Member
If you're going to take any exogenous cortisones on a continuous base, you should always take DHEA to balance it with.

if you're taking exogenous cortisones to fight adrenal fatigue, you shouldn't worry about reducing your body's own cortisol production, as this is the whole point of cortisol replacement therapy (using daily, small doses). You want to reduce the load on your adrenals so they don't get burned out and can keep up.
 

Mark Saur

Active Member
Yes, once my HPA seemed to settle down, Thyroid became much easier to tolerate. Dr. Mariano used to say.. the perfect test of HPA status is taking Thyroid hormone.

T3 alone just made my heart beat too fast and felt too ramped up. I convert T4 to T3 pretty well. So, I actually need a touch of Levothyroxine along with my daily NP Thyroid to get the right balance.
what is your current thyroid protocol?
 

wondering

Active Member
what is your current thyroid protocol?

25mcg Levothyroxine
90mg NP Thyroid - though it is really closer to 75mg or 60mg as I have to pinch a bit off. It works so I haven't asked my doc to lower the dose. I probably should and save a couple bucks.

But, we are all unique, you need to let labs and symptoms guide you.
 

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