ExcelMale Forum. TRT, Hormones, Peptides, Men’s Health

The Leading Men's Health Forum for Testosterone Optimization & Hormone Wellness

Welcome to ExcelMale.com — the most trusted, expert-moderated community for men seeking evidence-based guidance on testosterone replacement therapy (TRT), hormone optimization, and total wellness. Since 2010, we've helped thousands of men take control of their health.

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Why ExcelMale? Evidence-Based Men's Health Information You Can Trust

Navigating testosterone replacement therapy and hormone health can be overwhelming. Conflicting information, outdated medical advice, and unqualified opinions flood the internet. ExcelMale.com was created to cut through the noise — providing a rigorously moderated space where men share real experiences, backed by clinical research and guided by genuine expertise.

Whether you're exploring TRT for the first time, optimizing your current protocol, managing side effects like elevated hematocrit or estradiol, or seeking to preserve fertility with HCG therapy, our community offers the knowledge and support you need. We discuss everything from injection frequency and bloodwork interpretation to lifestyle factors that affect testosterone levels.

"I founded ExcelMale after decades of personal experience with hormone optimization and seeing how difficult it was for men to find reliable, science-based information. Every man deserves access to knowledge that can transform his quality of life."

— Nelson Vergel, Founder & Author of Testosterone: A Man's Guide

Nelson Vergel has spent four decades turning personal health challenges into a mission that's helped thousands of men reclaim their vitality. Diagnosed with HIV in 1985 and then creating a testosterone-based program to reverse wasting syndrome for himself and his peers, he became a pioneer in understanding how hormones affect quality of life—and has been on TRT himself for over 30 years.

A chemical engineer by training, Nelson has served as a key opinion leader for pharmaceutical companies on clinical research strategy, trained clinicians on hormone optimization protocols, and authored definitive guides including Testosterone: A Man's Guide & Beyond Testosterone. He founded DiscountedLabs.com to make lab testing accessible and built ExcelMale.com into a community where men find and share evidence-based answers.

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How to Predict Estradiol and DHT at Different Testosterone Doses
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I was able to come up with a table using the predictive model equation derived from data in this study: The Effects of Injected Testosterone Dose and Age on the Conversion of Testosterone to Estradiol and Dihydrotestosterone in Young and Older...
Does Testosterone Cause Prostate Cancer? Can Men Treated for Prostate Cancer Use TRT?
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This is an excerpt from my book Ensuring Prostate Health—No Link Found Between Androgen Levels and Risk for Prostate Cancer The prostate is a gland that is part of the male reproductive system. Its function is to store and secrete a slightly...

Sexual Medicine and Stem Cell Therapy: Everything You Need to Know

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How are stem cells related to sexual medicine? Find out in the first installment of Smart Sex, where sexual medicine providers answer the questions you want to know. Exploring Stem Cell Therapy for Erectile Dysfunction | Smart Sex Episode 1 ✦...
Treatments for Low Libido in Men
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The Potential for Pharmacological Interventions for Low Sex Drive in Men (2021) Amit G. Reddy, MD,1 Amelia A. Khoei, BS,2 and Mohit Khera, MD1 NTRODUCTION Despite numerous advancements in the field of sexual medicine, there remain a handful...
Can Testosterone Replacement Affect Kidneys?
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Creatinine is a chemical waste product that's produced by your muscle metabolism and to a smaller extent by eating meat. Healthy kidneys filter creatinine and other waste products from your blood. The filtered waste products leave your body in...
PT - 141 (Bremelanotide) for Improved Sex Drive (Libido) and Erections
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• Bremelanotide (PT 141) is a synthetic melanocortin compound • It is a ‘melanocortin receptor agonist’- activates melanocortin receptors in the body • ‘Melanocortins’ refer to a group of peptide hormones derived in the pituitary gland •...
Anti-Obesity Medications and Investigational Agents
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Anti-Obesity Medications and Investigational Agents: An Obesity Medicine Association (OMA) Clinical Practice Statement (CPS) 2022 Harold E. Bays, Angela Fitch, Sandra Christensen, Karli Burridge, Justin Tondt ABSTRACT Background: This...
Where to Get Therapeutic Phlebotomies to Lower High Hematocrit in the U.S.
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Understanding Therapeutic Phlebotomies to Lower High Hematocrit What is High Hematocrit? High hematocrit occurs when your body produces an increased number of blood cells, leading to thicker, more "viscous" blood. This condition strains the...
Post-Finasteride Syndrome and Upcoming Research
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Post-Finasteride Syndrome is the current term for a rare syndrome of devastating physical, neurological, and sexual side effects that persist and progress after stopping finasteride. The condition occurs primarily in younger men who have taken...
Managing Hair Loss: Comprehensive Review
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A review discusses various treatments for androgenetic alopecia (AGA), the most common cause of hair loss. Traditional methods like minoxidil and finasteride have mixed results. Newer treatments, such as low-level laser therapy (LLLT)...
Intranasal kisspeptin: a novel, effective, and non-invasive approach to stimulate reproductive hormones
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https://www.endocrine-abstracts.org/ea/0094/ea0094oc4.4 Background Kisspeptin is a potent regulator of GnRH neurons with the potential to treat reproductive and psychosexual disorders. However, administration is limited to the subcutaneous or...
Effect of Alcohol on Testosterone Blood Level
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Does anyone have any info about alcohol and TRT ? Is it true that while you are on TRT and consuming alcohol, your estrogen levels will rise?

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