Nelson Vergel

Nelson Vergel

Testosterone Replacement Enhances the Effects of Metformin on Lipids and Inflammation

Jun 01

Exp Clin Endocrinol Diabetes 2015; 123(10): 608-613 The Effect of Metformin and Metformin-Testosterone Combination on Cardiometabolic Risk Factors in Men with Late-onset Hypogonadism and Impaired Glucose Tolerance Abstract No...

Testosterone Reduces Fat by Decreasing Leptin Resistance

Jun 01

“The novelty in our study stems from the fact that we simultaneously investigated the effects of testosterone in the context of a rigorous weight-loss program,”Mathis Grossmann,MD,PhD,FRACP,professor in the department of medicine at the...

Exposure to Phthalates Decreases Testosterone and Sperm Quality in Men

Jun 01

Phthalates are used in a large variety of products, from enteric coatings of pharmaceutical tablets and nutritional supplements to viscosity control agents, gelling agents, film formers, stabilizers,dispersants, lubricants, binders, emulsifying...

Research Options for Erectile Dysfunction: Stem Cells and More

May 30

The best paper to date summarizing research therapies for ED. I highly recommend reading the full paper below (attached file- Register on ExcelMale to open it). Abstract: Although oral phosphodiesterase-5 (PDE5) inhibitors are...

Water Retention Caused by Testosterone May Have Nothing to Do with Estradiol

May 30

I get a lot of emails from men on testosterone replacement therapy (and/or HCG) that feel they have water retention (some with ankle swelling) and they are puzzled that their estradiol is low or below 35 micrograms/ml. They may have tried...

Testosterone Therapy Does Not Increase DVT and Pulmonary Embolism in 71,000 Patients

May 29

Association Between Testosterone Replacement Therapy and the Incidence of DVT and Pulmonary Embolism: A Retrospective Cohort Study of the Veterans Administration Database. Sharma R, et al. Chest. 2016. Abstract BACKGROUND...

Testosterone Therapy Increased Fat Loss During Low Calorie Diet in Obese Men with low T

May 29

Effects of testosterone treatment on body fat and lean mass in obese men on a hypocaloric diet: a randomised controlled trial. Ng Tang Fui M, et al. BMC Med. 2016. Abstract BACKGROUND: Whether testosterone treatment has benefits on...

Dihydrotestosterone- Man's Enemy or Friend ?

May 27

DHT – FRIEND OR ENEMY? With the exception of estradiol, no hormone is more misunderstood than dihydrotestosterone, DHT. In fact, many men actually fear DHT, going out of their way to lower it and frustrate its biological activity. However...

Global Testosterone Deficiency Diagnosis and Treatment Patterns

May 27

Although the measurement of serum testosterone levels is commonly used in the diagnosis of male HG, the cut-off values for low testosterone are not well defined and vary throughout the literature, ranging from 200–400 ng/dL, with 300 ng/dL being...

Testosterone Therapy Reduces Risk of Rehospitalization in Older Men With Low Testosterone.

May 26

Androgen Therapy and Rehospitalization in Older Men With Testosterone Deficiency. Baillargeon J, et al. Mayo Clin Proc. 2016. OBJECTIVE: To assess whether the receipt of androgen therapy is associated with a reduced 30-day...

How to reverse sexual dysfunction caused by antidepressants

May 26

In an open-label study of 1,022 patients with a mean 40 years of age, 59.1% reported antidepressant-associated sexual dysfunction.10 The study analyzed the following antidepressants: citalopram, paroxetine, venlafaxine, sertraline, fluvoxamine...

Comparison of testosterone clinics in the United States

May 10

This table summarizes the differences between men's health testosterone clinics on the following parameters: 1- Is insurance accepted? 2- Is 24 hr/7 day support provided? 3- Is there a free assessment? 4- Is there a travel credit for...

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038