XYOSTED Brand Refresh & Patient Experience

madman

Super Moderator


Supporting an established biopharmaceutical organisation, to ensure their groundbreaking Testosterone Replacement Therapy (TRT) stands out in a crowded market place.
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Halozyme is a biopharmaceutical company advancing disruptive solutions to improve patient experiences and outcomes for emerging and established therapies.

The organisation develops unique proprietary technology—and offers the first and only TRT weekly auto-injector of its kind; ‘XYOSTED’. This innovation allows male patients, who have low or no testosterone due to certain medical conditions to self-administer treatment with greater autonomy, a major leap forward in patient empowerment.




The Challenge

Despite the scientific breakthrough, XYOSTED faced a significant market challenge: standing out from its competitors in an industry crowded with legacy TRT methods, some of which have been standard since the 1960s. Their novel delivery method needed to be positioned as an appealing alternative —attractive in both clinical efficacy and patient experience.

With a sales team facing the pressures of delivering product benefits to time-pressured physicians the need for a compelling, benefit led and patient centric brochure was recognised along with the need for strategic overhaul of the brand.




Our Approach

We began with a strategic audit of the client’s brand, value proposition, and messaging, identifying key opportunities to elevate their positioning.

From there, we devised a multi-layered tactical rollout:

  • Developed engaging, persona-aligned patient collateral designed to compete with more established competitors.
  • High-impact 3D product visualisation and animation, allowing HCPs and patients to fully understand the unique mechanism of action.
  • Strategic design balanced with FDA-compliant medical copywriting, to account for sensitive integration of regulatory requirements such as ‘Black Boxed Warnings’.*
  • Device-agnostic, accessible design across both print and digital formats.
  • Liaised with client-preferred, international vendor in respect to high-quality print.

*Black Boxed Warning for XYOSTED was <a href="FDA issues class-wide labeling changes for testosterone products">removed by the FDA in February 2025</a>



Results & Next Steps

To date, the response is hugely encouraging. The new Patient Brochure was met with enthusiastic feedback from the sales team at the client’s National Sales Meeting in February 2025 and the asset has been rolled out across the organisation.

Building on this success, we’ve been commissioned to continue the digital journey with a new project. This next phase will draw on our expertise in digital strategy, UX/UI, stakeholder management, and brand storytelling, bringing consistent excellence across every channel.
 




XYOSTED- testosterone enanthate injectionAntares Pharma, Inc.

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hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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