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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
What needle length for IM TRT? Thinking of changing from subQ to IM to feel better
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<blockquote data-quote="Blackhawk" data-source="post: 185799" data-attributes="member: 16042"><p>It is not as simple as achieving a certain blood level. Once steady state blood level is reached it still takes quite some time for your body to adapt to that "new normal" blood level. That adaptation takes time.</p><p></p><p>And this adaptation is not linear, homogeneous or fully predictable in all individuals. And there is much still to be learned. There are too many variables: what is SHBG?, how much is being converted into estrogen? How much is bound by albumin? How sensitive are your cell receptors, and how much will cell receptor number and function be affected by change in blood plasma level of Testosterone? How long does it take receptors to stabilize in response to the "new normal" level of blood testosterone? How are the downstream effects of the cellular uptake of testosterone affected and how long does it take for them to normalize? How do your cells vs my cells respond? What potential genetic polymorphisms may be involved? How does T affect protein synthesis as it interacts with DNAin cellular metabolism? What other cellular processes are affected?... etc etc...</p></blockquote><p></p>
[QUOTE="Blackhawk, post: 185799, member: 16042"] It is not as simple as achieving a certain blood level. Once steady state blood level is reached it still takes quite some time for your body to adapt to that "new normal" blood level. That adaptation takes time. And this adaptation is not linear, homogeneous or fully predictable in all individuals. And there is much still to be learned. There are too many variables: what is SHBG?, how much is being converted into estrogen? How much is bound by albumin? How sensitive are your cell receptors, and how much will cell receptor number and function be affected by change in blood plasma level of Testosterone? How long does it take receptors to stabilize in response to the "new normal" level of blood testosterone? How are the downstream effects of the cellular uptake of testosterone affected and how long does it take for them to normalize? How do your cells vs my cells respond? What potential genetic polymorphisms may be involved? How does T affect protein synthesis as it interacts with DNAin cellular metabolism? What other cellular processes are affected?... etc etc... [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
What needle length for IM TRT? Thinking of changing from subQ to IM to feel better
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