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Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
What is the reason that nandrolone causes depression? (Mechanism of action)
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<blockquote data-quote="t_spacemonkey" data-source="post: 268635" data-attributes="member: 44502"><p>when my deca experience went south, I noticed that adding an AI did not improve any symptoms at all. i still think that there is some dopaminergic activity which causes the issues, maybe indirectly. that why dopamine agonist fixed the issue. </p><p>it took me exactly 3 weeks after the last deca injection for all symptoms to clear. the way i can tell for sure, is then as mentioned earlier, a dopamine agonist called pramipexole fixed those issues essentially instantly. pramipexole with a short half life of 8h wears of within a day or so max. I stopped the drug mid-way (10 days into deca) and all symptoms returned very quickly. first i thought it might be a pure pami withdrawal. i restarted prami, however at week 3, i stopped it again and got no issues whatsoever libido returning to baseline and mood ok. </p><p>prami is an amazing libido booster, but can't be used daily IMO for various reasons. but if you need a weekend boost, prami+cialis will do crazy things.</p><p>the only part i miss about deca, is that it rather feels calming (but with issues as above) and the gym performance definitely goes up, recovery way better etc. might try NPP some time in the future</p></blockquote><p></p>
[QUOTE="t_spacemonkey, post: 268635, member: 44502"] when my deca experience went south, I noticed that adding an AI did not improve any symptoms at all. i still think that there is some dopaminergic activity which causes the issues, maybe indirectly. that why dopamine agonist fixed the issue. it took me exactly 3 weeks after the last deca injection for all symptoms to clear. the way i can tell for sure, is then as mentioned earlier, a dopamine agonist called pramipexole fixed those issues essentially instantly. pramipexole with a short half life of 8h wears of within a day or so max. I stopped the drug mid-way (10 days into deca) and all symptoms returned very quickly. first i thought it might be a pure pami withdrawal. i restarted prami, however at week 3, i stopped it again and got no issues whatsoever libido returning to baseline and mood ok. prami is an amazing libido booster, but can't be used daily IMO for various reasons. but if you need a weekend boost, prami+cialis will do crazy things. the only part i miss about deca, is that it rather feels calming (but with issues as above) and the gym performance definitely goes up, recovery way better etc. might try NPP some time in the future [/QUOTE]
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Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
What is the reason that nandrolone causes depression? (Mechanism of action)
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