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Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
What is the reason that nandrolone causes depression? (Mechanism of action)
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<blockquote data-quote="captain_j" data-source="post: 268620" data-attributes="member: 40998"><p>I've also tried using nandrolone (NPP or Deca at different times) along with my TRT. My test dose has ranged over the years from 110 mg a week up to 200 mg a week. I've tried different amounts of nandrolone with the test, from 70 mg up to 200 mg per week. I also can say that it has a negative effect on my mood as well. I was injecting my test daily for years because it's how I thought I felt best, but a few weeks ago decided to go to every 3.5 days to allow those small gaps in time so that my test can be on the decline and allow my receptors time to take a break. Logic was telling me that keeping my test ruler flat at redline 24/7/365 may not be a good thing, since I have been experiencing fewer benefits from TRT over the last year or so, and I've been on it since Oct 2019. It's been an interesting experiment to see how I feel after 3-3.5 days when my test levels are dropping. It's a feeling I haven't experienced since starting TRT. What I would like to try is making alternating my injections. So Tuesday morning inject 100 mg nandrolone, then 3.5 days later (Friday PM) inject 100 mg testosterone. This could either make me feel absolutely horrible or maybe it would be beneficial. That's one thing I'd like to try, or perhaps doing what others have suggested here, and going with a very low test base of 40 mg test per week, and 120 mg nandrolone on top of that. </p><p></p><p>I think estrogen levels have a big impact on how you feel with nandrolone. I've read conflicting things about how much nandrolone will aromatize (if at all), but there are theories that somehow it can cause your body to become more sensitive to estrogen in general. This may be due to the progesterone effect of nandrolone. So you say your e2 sensitive is under control at 25 ng/dl, then you introduce nandrolone. Even if your e2 stays around 25, the nandrolone might make it feel like a 60-70 because you're now more sensitive to it. For me personally, I do not react well to elevated estrogen. I've found out many times now that it makes me feel like absolute garbage mentally. I think this may also be why I don't do well on nandrolone combined with normal TRT levels of test. It's another reason why a very low test base might combine well with nandrolone for me and others, and is something I'd like to try.</p></blockquote><p></p>
[QUOTE="captain_j, post: 268620, member: 40998"] I've also tried using nandrolone (NPP or Deca at different times) along with my TRT. My test dose has ranged over the years from 110 mg a week up to 200 mg a week. I've tried different amounts of nandrolone with the test, from 70 mg up to 200 mg per week. I also can say that it has a negative effect on my mood as well. I was injecting my test daily for years because it's how I thought I felt best, but a few weeks ago decided to go to every 3.5 days to allow those small gaps in time so that my test can be on the decline and allow my receptors time to take a break. Logic was telling me that keeping my test ruler flat at redline 24/7/365 may not be a good thing, since I have been experiencing fewer benefits from TRT over the last year or so, and I've been on it since Oct 2019. It's been an interesting experiment to see how I feel after 3-3.5 days when my test levels are dropping. It's a feeling I haven't experienced since starting TRT. What I would like to try is making alternating my injections. So Tuesday morning inject 100 mg nandrolone, then 3.5 days later (Friday PM) inject 100 mg testosterone. This could either make me feel absolutely horrible or maybe it would be beneficial. That's one thing I'd like to try, or perhaps doing what others have suggested here, and going with a very low test base of 40 mg test per week, and 120 mg nandrolone on top of that. I think estrogen levels have a big impact on how you feel with nandrolone. I've read conflicting things about how much nandrolone will aromatize (if at all), but there are theories that somehow it can cause your body to become more sensitive to estrogen in general. This may be due to the progesterone effect of nandrolone. So you say your e2 sensitive is under control at 25 ng/dl, then you introduce nandrolone. Even if your e2 stays around 25, the nandrolone might make it feel like a 60-70 because you're now more sensitive to it. For me personally, I do not react well to elevated estrogen. I've found out many times now that it makes me feel like absolute garbage mentally. I think this may also be why I don't do well on nandrolone combined with normal TRT levels of test. It's another reason why a very low test base might combine well with nandrolone for me and others, and is something I'd like to try. [/QUOTE]
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Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
What is the reason that nandrolone causes depression? (Mechanism of action)
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