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Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
What is the reason that nandrolone causes depression? (Mechanism of action)
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<blockquote data-quote="Gman86" data-source="post: 267653" data-attributes="member: 15043"><p>With low doses that we would be taking for optimization purposes/ lowering prolactin/ increasing dopamine purposes, and not using it as a full blown depression treatment, there’s literally nothing to worry about. I think that stuff about avoiding cheese and certain foods is really overblown. All I’ve heard is anecdotes of people never having interactions with those certain foods while on it. Never once heard of a person having a reaction from the foods they say to stay away from while on it</p><p></p><p>and supposedly its one of the very very few longevity/ anti-aging medications. It supposedly helps slow the aging process, and increases longevity. So it seems like not only is it not dangerous to take long term, but it’s actually beneficial to do so. Im just not sure if there’s any issues with dipping below baseline, as far as dopamine levels go, if discontinuing it after taking it for an extended time. I’ve never heard or read anything about that happening, it’s just a personal concern/ thought. With every high, there’s usually a low. There’s usually no biological free lunches. But I’ve personally never noticed a decline from baseline when stopping, and never heard of anyone reporting this happening</p><p></p><p>dosages vary depending whether u plan on taking it sublingually or orally. Supposedly taking It sublingually increases absorption by up to 8x. I’ve seen a ton of anecdotes of guys using 1.25mg ED, EOD, or twice per week, sublingually, and then guys like [USER=38526]@BadassBlues[/USER] takes 5mg orally ED, and reports that being a really good dose for him. Probably don't need more than 5-10mg orally ED, and sublingually u probably don’t need more than 1.25-2.5mg ED</p><p></p><p>and I think the half life is pretty long. So</p><p>its not something thats in and out like prami. It’s the opposite. Takes a while to feel the effects, and takes a while for the enzyme that it blocks to build back up. Have this quote saved about it</p><p></p><p>“The body naturally gets rid of & synthesizes new enzymes, so in some time, the MAO-B would replenish if you halted use. It's said to take around 45 days for the inhibition to halve, then another 45 days for the remaining half to halve, etc.”</p><p></p><p>and someone also stated this about the half life </p><table class='post-table ' style='width: 100%'><tr><td ><p><br /> <a href="https://www.reddit.com/user/dmt-entity-but-irl/" target="_blank">dmt-entity-but-irl</a><br /> 1y</p></td><td></td></tr></table>down regulated dopamine does not equal parkinson’s. sounds like the selegiline is giving you some anxiety? sine it takes 45 days for the enzyme to regenerate, you could just take it once every 2 weeks or so and the mao-b inhibitor would be similar.</p></blockquote><p></p>
[QUOTE="Gman86, post: 267653, member: 15043"] With low doses that we would be taking for optimization purposes/ lowering prolactin/ increasing dopamine purposes, and not using it as a full blown depression treatment, there’s literally nothing to worry about. I think that stuff about avoiding cheese and certain foods is really overblown. All I’ve heard is anecdotes of people never having interactions with those certain foods while on it. Never once heard of a person having a reaction from the foods they say to stay away from while on it and supposedly its one of the very very few longevity/ anti-aging medications. It supposedly helps slow the aging process, and increases longevity. So it seems like not only is it not dangerous to take long term, but it’s actually beneficial to do so. Im just not sure if there’s any issues with dipping below baseline, as far as dopamine levels go, if discontinuing it after taking it for an extended time. I’ve never heard or read anything about that happening, it’s just a personal concern/ thought. With every high, there’s usually a low. There’s usually no biological free lunches. But I’ve personally never noticed a decline from baseline when stopping, and never heard of anyone reporting this happening dosages vary depending whether u plan on taking it sublingually or orally. Supposedly taking It sublingually increases absorption by up to 8x. I’ve seen a ton of anecdotes of guys using 1.25mg ED, EOD, or twice per week, sublingually, and then guys like [USER=38526]@BadassBlues[/USER] takes 5mg orally ED, and reports that being a really good dose for him. Probably don't need more than 5-10mg orally ED, and sublingually u probably don’t need more than 1.25-2.5mg ED and I think the half life is pretty long. So its not something thats in and out like prami. It’s the opposite. Takes a while to feel the effects, and takes a while for the enzyme that it blocks to build back up. Have this quote saved about it “The body naturally gets rid of & synthesizes new enzymes, so in some time, the MAO-B would replenish if you halted use. It's said to take around 45 days for the inhibition to halve, then another 45 days for the remaining half to halve, etc.” and someone also stated this about the half life [TABLE][TR][TD] [URL='https://www.reddit.com/user/dmt-entity-but-irl/']dmt-entity-but-irl[/URL] 1y [/TD] [TD] [/TD][/TR][/TABLE] down regulated dopamine does not equal parkinson’s. sounds like the selegiline is giving you some anxiety? sine it takes 45 days for the enzyme to regenerate, you could just take it once every 2 weeks or so and the mao-b inhibitor would be similar. [/QUOTE]
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Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
What is the reason that nandrolone causes depression? (Mechanism of action)
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