madman
Super Moderator
Must listen for anyone interested in fertility especially when using exogenous T!
* Why lab work and semen analysis interpretation require true infertility expertise
In this exciting episode of Fertility and Other F Words, Dr. Amy Pearlman and Dr. Larry Lipshultz are joined by two leaders in male reproductive medicine: Dr. Blair T. Stocks and Dr. Taylor Kohn.
Dr. Stocks and Kohn are Assistant Professors of Urology in the Division of Male Reproductive Medicine and Surgery at Baylor College of Medicine. Both specialize in the evaluation and treatment of men presenting with infertility.
Together, we walk through what a thorough male fertility evaluation actually looks like—from history and physical exam to lab work and imaging—and discuss cutting-edge research and innovative techniques being used to better understand why some men present with infertility and how sperm may still be found in men who’ve been told they have none.
This episode dives deep into:
* How male fertility is evaluated in real clinical practice
* Why lab work and semen analysis interpretation require true infertility expertise
* What azoospermia really means—and why it doesn’t always mean “no options”
* Emerging technologies helping specialists find sperm with greater precision
Key Takeaways
Semen analysis is an important metric of a man’s health. At-home semen analysis testing can be used as a screening tool.
In-office semen analysis and hormonal blood work are core parts of the evaluation and blood work may include:
- Total testosterone
- Free testosterone
- FSH
- LH
- Inhibin B
- Anti-Müllerian Hormone (AMH)
- 17-hydroxyprogesterone (17-OH progesterone)
- Prolactin
- Estradiol
* Interpretation of semen analysis and lab results should be done by an expert in male infertility.
* Men told they have azoospermia (no sperm in the ejaculate) may still have additional options.
* There are currently no FDA-approved medications for male infertility
* A healthy lifestyle—nutrition, movement, and overall wellness—matters for sperm health
Innovative Research Highlighted
Dr. Taylor Kohn is using high-frequency ultrasound to identify areas of the testicle more likely to contain sperm by visualizing dilated seminiferous tubules—helping guide sperm extraction procedures with greater precision and potentially less invasiveness.
Dr. Blair Stocks is using flow cytometry to determine whether men told they have “no sperm” truly have none, allowing rapid identification of rare sperm cells that may otherwise be missed.
* Why lab work and semen analysis interpretation require true infertility expertise
In this exciting episode of Fertility and Other F Words, Dr. Amy Pearlman and Dr. Larry Lipshultz are joined by two leaders in male reproductive medicine: Dr. Blair T. Stocks and Dr. Taylor Kohn.
Dr. Stocks and Kohn are Assistant Professors of Urology in the Division of Male Reproductive Medicine and Surgery at Baylor College of Medicine. Both specialize in the evaluation and treatment of men presenting with infertility.
Together, we walk through what a thorough male fertility evaluation actually looks like—from history and physical exam to lab work and imaging—and discuss cutting-edge research and innovative techniques being used to better understand why some men present with infertility and how sperm may still be found in men who’ve been told they have none.
This episode dives deep into:
* How male fertility is evaluated in real clinical practice
* Why lab work and semen analysis interpretation require true infertility expertise
* What azoospermia really means—and why it doesn’t always mean “no options”
* Emerging technologies helping specialists find sperm with greater precision
Key Takeaways
Semen analysis is an important metric of a man’s health. At-home semen analysis testing can be used as a screening tool.
In-office semen analysis and hormonal blood work are core parts of the evaluation and blood work may include:
- Total testosterone
- Free testosterone
- FSH
- LH
- Inhibin B
- Anti-Müllerian Hormone (AMH)
- 17-hydroxyprogesterone (17-OH progesterone)
- Prolactin
- Estradiol
* Interpretation of semen analysis and lab results should be done by an expert in male infertility.
* Men told they have azoospermia (no sperm in the ejaculate) may still have additional options.
* There are currently no FDA-approved medications for male infertility
* A healthy lifestyle—nutrition, movement, and overall wellness—matters for sperm health
Innovative Research Highlighted
Dr. Taylor Kohn is using high-frequency ultrasound to identify areas of the testicle more likely to contain sperm by visualizing dilated seminiferous tubules—helping guide sperm extraction procedures with greater precision and potentially less invasiveness.
Dr. Blair Stocks is using flow cytometry to determine whether men told they have “no sperm” truly have none, allowing rapid identification of rare sperm cells that may otherwise be missed.
History of testosterone therapy through the ages (2022)
Mary Rostom, Ranjith Ramasamy, and Taylor P. Kohn
The symptoms of testosterone deficiency have been known throughout history with evidence dating back to the twenty-first century BCE when men were castrated to be docile and obedient servants. Experimentation ingesting mammalian testicles began during the reign of the Roman empire and continued through the nineteenth century with claims that the substance found within these testicles could improve energy, erectile function, and urination. In the twentieth century, studies...
Mary Rostom, Ranjith Ramasamy, and Taylor P. Kohn
The symptoms of testosterone deficiency have been known throughout history with evidence dating back to the twenty-first century BCE when men were castrated to be docile and obedient servants. Experimentation ingesting mammalian testicles began during the reign of the Roman empire and continued through the nineteenth century with claims that the substance found within these testicles could improve energy, erectile function, and urination. In the twentieth century, studies...
- madman
- testosterone
- Replies: 4
- Forum: Testosterone Basics & Questions
Management of Erythrocytosis in Men Receiving Testosterone Therapy: Clinical Consultation Guide (2022)
Pranjal Agrawal, Sajya M. Singh, Taylor Kohn
1. Introduction
Testosterone deficiency, previously known as male hypogonadism, affects approximately 25% of all men, with a prevalence that increases with age [1]. Risk factors for developing adult-onset testosterone deficiency include obesity, chronic disease, and poor general health [2]. Individuals with clinical hypogonadal symptoms and two-morning samples demonstrating low testosterone levels often...
Pranjal Agrawal, Sajya M. Singh, Taylor Kohn
1. Introduction
Testosterone deficiency, previously known as male hypogonadism, affects approximately 25% of all men, with a prevalence that increases with age [1]. Risk factors for developing adult-onset testosterone deficiency include obesity, chronic disease, and poor general health [2]. Individuals with clinical hypogonadal symptoms and two-morning samples demonstrating low testosterone levels often...
- madman
- testosterone therapy; erythrocytosis
- Replies: 2
- Forum: Testosterone Side Effect Management
* Human chorionic gonadotropin (hCG) therapy can be co-administered with TTh to maintain spermatogenesis, testicular size, or libido, but no study has assessed associated 17-OHP levels in these men on concurrent TTh and hCG therapy. levels in men on TTh.
* In our practice, hCG 1500 IU subcutaneous injection is prescribed once weekly to maintain spermatogenesis while on TTh, 1500 IU twice weekly to restore testicular size or improve libido while on TTh, or 3000 IU three times weekly plus FSH and TTh when attempting to reboot spermatogenesis after TTh therapy allowing...
* In our practice, hCG 1500 IU subcutaneous injection is prescribed once weekly to maintain spermatogenesis while on TTh, 1500 IU twice weekly to restore testicular size or improve libido while on TTh, or 3000 IU three times weekly plus FSH and TTh when attempting to reboot spermatogenesis after TTh therapy allowing...
- madman
- hcg; 17-ohp; fertility; spermatogenesis
- Replies: 1
- Forum: hCG, Clomid & Others for Fertility, PCT or Low T
* Univariate analysis showed that poor metabolizers had the greatest improvements in luteinizing hormone (LH), follicle-stimulating hormone (FSH), and sperm concentration (Figures 1 and 2, p<0.05). There was no statistical difference in testosterone level. Multivariate linear regression indicated that age, clomiphene vs enclomiphene use, baseline hormone levels and sperm concentration were not associated with response (p>0.05), however, metabolizer status significantly predicted increases in LH, FSH, and sperm concentration (p<0.05).
* Infertile...
* Infertile...
- madman
- hypogonadism; clomid/enclomiphene; adverse events
- Replies: 0
- Forum: hCG, Clomid & Others for Fertility, PCT or Low T
* All included men had demonstrated fertility prior to vasectomy. The two reboot protocols included: hCG 3000 IU three times weekly, plus either enclomiphene/clomiphene 25 mg daily or FSH 75 IU three times weekly. A negative control group of men who had undergone TESA while on concurrent testosterone therapy without a reboot protocol was also identified
* Reinduction of spermatogenesis, or reboot, with either hCG+SERM or hCG+FSH appears to be successful, among men with proven prior fertility.
COMPARING REBOOT PROTOCOL FOR...
* Reinduction of spermatogenesis, or reboot, with either hCG+SERM or hCG+FSH appears to be successful, among men with proven prior fertility.
COMPARING REBOOT PROTOCOL FOR...
- madman
- vasectomy; fertility;/sperm; hcg reboot
- Replies: 0
- Forum: hCG, Clomid & Others for Fertility, PCT or Low T