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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
What’s the general consensus on AI’s here?
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<blockquote data-quote="Cataceous" data-source="post: 161027" data-attributes="member: 38109"><p>This reference also has a potentially significant weakness in that the study used ECLIA to measure estradiol; they may have been measuring some CRP along with estradiol.</p><p></p><p>Nonetheless, with respect to cholesterol, I have not yet come across evidence that AIs cause unfavorable changes independent of their effects on estradiol.</p><p></p><p>I don't disagree with your main point: it's an open question as to whether we should be concerned about the results of AI studies using ~20 times more than typical TRT doses. But this must be balanced against the other extreme, which is males having estradiol levels basically not seen in nature. It might be tempting to say that it's probably ok because women experience high levels all the time. But there is some cellular-level research showing that in some cases male and female responses to estradiol can be quite different, with the effects on males being potentially harmful.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 161027, member: 38109"] This reference also has a potentially significant weakness in that the study used ECLIA to measure estradiol; they may have been measuring some CRP along with estradiol. Nonetheless, with respect to cholesterol, I have not yet come across evidence that AIs cause unfavorable changes independent of their effects on estradiol. I don't disagree with your main point: it's an open question as to whether we should be concerned about the results of AI studies using ~20 times more than typical TRT doses. But this must be balanced against the other extreme, which is males having estradiol levels basically not seen in nature. It might be tempting to say that it's probably ok because women experience high levels all the time. But there is some cellular-level research showing that in some cases male and female responses to estradiol can be quite different, with the effects on males being potentially harmful. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
What’s the general consensus on AI’s here?
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