Vulnerability to Fructose Varies, Health Study Finds

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Nelson Vergel

Fructose, a sugar widely consumed in the form of high-fructose corn syrup, may promote obesity and diabetes by overstimulating a hormone that helps to regulate fat accumulation, researchers reported on Monday.

The study, carried out at Harvard Medical School, marks the first time that scientists have identified a hormone that rises sharply and consistently in response to eating fructose. The finding suggests that people may vary in their sensitivity to the sugar, and that eventually it may be possible to test an individual for susceptibility to illnesses linked to weight gain.

Fructose stimulated the sharpest rise in the hormone in people who were obese, an increase that the researchers believe may trigger resistance to its effects, according to the study, which was published in the journal Molecular Metabolism. But even among lean people, there was wide variation in this response.

Vulnerability to Fructose Varies, Health Study Finds
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Nelson Vergel

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