Vitamin K2

Ardoc

Member
Does anyone know if taking Vitamin K2 is contraindicated in men receiving TRT? I read that warning on a bottle of K2 once but have never seen it again (even on the same brand) and searching online has provided no answers. Since it seems K2 is important in conjunction with D3, especially for bone strength, it is a supplement I am interested in taking.

I realize if you have polycythemia that a clotting factor like vitamin K may not be good, but I do regular bloodwork and donate blood to keep my hematocrit below 50%.

Thanks in advance!
 
K2 with TRT is fine unless you are on prescription blood thinner(s). So many people are on Warfarin and other blood thinners these days that they have to put a warning on the bottles.
 
Thanks ERO! The warning essentially said 'men should not take this while on Testosterone Therapy'? I have seen the warning about blood thinners as well and that seems to be on all K2 supplements that I've seen. The warning on that one brand though made me throw out the product and I wish I still had the container at least. It was only troublesome because it was so specific to my situation. Do you know of any resources that elaborate on this?
 
I would bet that is because of the recent (and recently debunked) scare about TRT causing heart attacks. See Nelson's post here

I am a study with a population size of 1, but I have used K2 for years while on TRT and I have no issues, nor any red-flags on my blood work because of it. I am also not on any prescription blood thinners or high BP meds, though.
 
Thanks again! I also take none of those drugs and I do realize many "studies" regarding TRT do not consider whether sides are managed or not. If they are not managed maybe it would be a concern? However thanks to resources like this I closely monitor all blood work. I appreciate your feedback.
 
Vit K does increse the clotting agent in the blood, would taking K with H&H on the high side or above be really safe?

K2 with TRT is fine unless you are on prescription blood thinner(s). So many people are on Warfarin and other blood thinners these days that they have to put a warning on the bottles.
 
I supplement with a vitamin K complex, for years. I've never had any problems but I'm not on any blood thinners.
 

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This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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