Vitamin D and Insulin Resistance

[CoastWatcher]

Researchers recently conducted a study to determine the clinical utility in measuring Vitamin D serum levels - along with other traditional risk-factor measurements - in the diagnosis of insulin resistance. Additionally, they worked to estimate the optimal D levels associated with normal glucose and insulin homeostasis.

• A cross-sectional analysis of 6,868 adults without diagnosed diabetes formed the sample group.
• Using logistic regression, two risk models were developed to estimate the risk of insulin resistance.
  • Model One included established risk factors
  • Model Two additionally included serum levels of Vitamin D.
• Model Two, the model including Vitamin D levels, marginally improved detection of insulin resistance. Adding Vitamin D levels to the calculation would identify an additional two to four cases per1,000 people.
• Model Two also determined that the lower Vitamin D threshold was estimated at 60 nmol/L.

It should be noted that the threshold differed by ethnicity and more testing is called for.

Diabetes Research and Clinical Practice, 2017 September 23
https://www.ncbi.nlm.nih.gov/m/pubmed/28951344/

 

[Cery32]

so is this saying that taking higher doses of vitamin d increases insulin sensitivity?