VIDEO: Testosterone Trials results announcement met with anticipation

Nelson Vergel

Founder, ExcelMale.com
In this video exclusive, Tamara Wexler, MD, PhD, director of the pituitary center at New York University Langone, give her perspective on the presentation involving results from the Testosterone Trials.
According to Wexler, the results were highly anticipated because of the design of the trial.
“Much of the previous information [on testosterone replacement] we had was from observational studies or with a less carefully controlled randomized population,” Wexler said. “It is important to note that the results of this study, as with any study, should be considered in the context of the particular cohort being studied.”
Results of the study were published last month in The New England Journal of Medicine.

http://www.healio.com/endocrinology...ls-results-announcement-met-with-anticipation
 

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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