*dictated. Forgive grammar and syntax errors.
Hi Jay. Nothing useful to report. Still working it all out. But one day if and when I get sorted I’ll bring my experience here. I’m off testosterone for now. Ergogenics and energy on trt we’re the only thing that seemed to be improved. Main purpose was for energy, mood and most of all libido and sexual consistency. Got off trt in May I think. Waited two weeks to dry out then started Working with enclomiphene 12.5mg mwf, anastrozole 0.1mg mwf,. Labs on spreadsheet from July.
Only time I had proper consistent libido and on demand erectile function in whole time on HRT was for 6-8wk on enclo protocol as above. BUT mood was way off. Tired, anxious, anhedonic. However there was a lot going on in life. So it’s impossible to say what caused the mood issues. One or the other or both.
I made a spreadsheet of my experience so far. Strange journey. Would chop off one of my toes for a clear path forward. Wish I could offer clear advice on what works for sure. Low progesterone, and allopregnenolone and other issues likely a component. Not sure how the androgens and neurosteroids all fit yet. But I do suspect that they are a component in being able to tolerate and fully benefit from TRT for me. From previous propecia use I likely have low five AR activity or density. Just not sure if pills, creams, injections of progesterone or pregnenolone or appropriate or what the dosing schedule, testing regimen etc. would be.
Nothing has seemed to truly stick yet. That six week of normal sexual function on enclo were fascinating. Wonder why.
Problem started when at about 6-7 weeks ON ENCLO/ANA I decided to stop the anast without labs because I was wondering if it was the depressant factor. The labs from July were taken before I did this. Then after a week off ana, only on ENCLO, having normal MW and masturbatory ability, OVERNIGHT/same day, went from strong morning erection and ability to what felt like a sympathetic stress response when masturbating that evening— palpitations, a little anxiety and then loss of erection and desire. Happened literally same day. That continued. Crash or some strange reaction of sort. Felt that along time ago when I was not on therapy. High estrogen low androgens low Neuro steroids some combination? I have no idea because I don’t have labs from those events.
Possible e2 overload sx or some kind of androgen or e2 receptor issue. Previous propecia user. Idk.
Meeting with Saya this week. Got labs last week after 2wk on basically nothing besides some progesterone cream from NOW on scrotum.
Back on enclo/ana 12.5mg/0.1mg mwf. Dhea 25hs. Other defy doc wanted me on the above Daily. Will run by Saya.
Want to make this process scientific. Regimented. Control variable etc. tired of the nonsense.