TRT with estrogen tablet

Nekos402

New Member
TRT replacement - there are a few similar posts but this might be unique. 54 y/o male. Male menopause symptoms started in Dec 2022. TRT started April 2023 0.7ml/200mg of TRT. Felt great. A year later, started estradiol, 1mg per week, decreased to 0.5 mg TRT. October 2024, Doc increased estradiol to 2x per week. Through me off mentally and physically. Doc had me stop cold turkey end of October. Felt ok, then felt fantastic - felt 15 years younger. 20 days after I stopped I experienced a level of anger - out of the blue - I've never felt before. Took my TRT shot the next day, but only 0.3 of TRT. Today, had the feeling of the unexplained anger again, but did not last but 2 hours. Called a friend (physician) and recommended I take 1mg of estradiol (my doc was not in). Last blood test at the end of October before I stopped taking estradiol Free Testosterone was 1500. Estrogen was 15.4.
 
TRT started April 2023 0.7ml/200mg of TRT. Felt great. A year later, started estradiol, 1mg per week, decreased to 0.5 mg TRT. October 2024, Doc increased estradiol to 2x per week.
If you feel great, why did your doctor make a change to your TRT protocol?

Took my TRT shot the next day, but only 0.3 of TRT.
You need to learn to better communicate your dosing, .3 of TRT is meaningless.

Where is the question?
 
If you feel great, why did your doctor make a change to your TRT protocol?


You need to learn to better communicate your dosing, .3 of TRT is meaningless.

Where is the question?
Not sure why the doc changed things up on me. The last dose was 0.3ml. And I've found the last few weeks difficult to sleep - knowing a high free testosterone can cause trouble sleeping.
 

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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

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Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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