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ED, loss of sensitivity, leg edema, loss of libido. I was trying to fix those issues by taking pt141 which did help a little but once i stopped the hcg everything resolved with only taking testosterone. Everything is great with only fertility being the issue. I haven't experienced any side effects from testosterone - no loss of testicle size etc and i was on it for more than a year so I'm hoping they're still producing sperm to help impregnate my wife. Good luck!