with EOD, like I do about 50-55mg, that's how I got off Anastrozole entirely but my E is by the standard test still in the 43 range and I have no high E symptoms either. Remember the larger the dose the more that is excess and is suceptible to the aromatase enzyme. It seems that everyone that goes smaller and more frequent is able to either get off entirely or go very low dose AI. Your E2 is curiously low and being supported by multiple tests is a curiosity. Some men do indeed experience differing E levels with IM and SubQ. You'll have to decide what you want to do, I might suggest you stay the same doses but go back IM (or shallow IM) and by doing that you'll limit the variable by only changing one thing. I think if you switch to IM, change your dose, change your frequency, you're introducing too many variables at one-time.