TRT Newbie Frustrated but Hopeful

Thanks Leesto - and others - for a interesting thread. I had a E2 crash this fall myself and it's been quite a struggle ever since. One of the things that I noticed, with the use of an AI, is how your need for it may change greatly with only few variables. For example I lost a about 5 pounds in few months and it seemed that it completely changed my former dosing protocol.

At the moment im still trying to get a hold on my current need of an AI. There are still few symptoms that seem to linger despite better E2 readings. These symptoms are mainly related to low dopamine - low libido, apathy, anhedonia etc. Im hoping that with time these symptoms will subside.
 
Thanks Leesto - and others - for a interesting thread. I had a E2 crash this fall myself and it's been quite a struggle ever since. One of the things that I noticed, with the use of an AI, is how your need for it may change greatly with only few variables. For example I lost a about 5 pounds in few months and it seemed that it completely changed my former dosing protocol.

At the moment im still trying to get a hold on my current need of an AI. There are still few symptoms that seem to linger despite better E2 readings. These symptoms are mainly related to low dopamine - low libido, apathy, anhedonia etc. Im hoping that with time these symptoms will subside.

Sounds like your E2 is still low.

Have you made a post with your recent labs?
 
Just curious simeoni why you're taking an AI at all when you recently crashed and you don't seem to have any high E2 symptoms?
 

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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

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Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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