Too much T3 causing high blood pressure?

mcs

Member
Known side effect of excess T3. So I've been on 162.5mg (2.5 grains) first thing in a.m. on empty stomach. Observing elevated systolic BP, but normal diastolic, normal HR.

Although TSH is optimized, I am wondering if the isolated systolic hypertension if from the peak plasma concentration of FT3 and if I should split up the dosing.

Labs:
TSH: 1.06
FT3: 5.3 Reference Range: 2.3-4.2 pg/mL
FT4: 1.1

Thoughts?
 
Why are you running it so high? Have you tested reverse T3? are these labs done 24 hours after your last dose? I would feel uncomfortable with T3 that high. How do you feel? You do not give your actual BP##.
 
Why are you running it so high? Have you tested reverse T3? are these labs done 24 hours after your last dose? I would feel uncomfortable with T3 that high. How do you feel? You do not give your actual BP##.
The goal was to optimize TSH. That was the only # that was off. rT3 averages about 15. Feel ok. I just think systolic is a little higher than I'd like (135-140); diastolic in the high 70s. I will report back with my split trial and see if my a.m. systolic reading drops from less T3 from the NDT all at once.
 
The goal was to optimize TSH. That was the only # that was off. rT3 averages about 15. Feel ok. I just think systolic is a little higher than I'd like (135-140); diastolic in the high 70s. I will report back with my split trial and see if my a.m. systolic reading drops from less T3 from the NDT all at once.
How long after your last dosage of thyroid was that test done? If you have thyroid disease the problem with tsh testing the interference is antibodies and so is free t3. Also the standard free t3 test has interference with binding globulins . A much better test is am, (before you take thyroid meds) free t3 dialysis- much more accurate
 

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Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

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