The Truth About Peyronie's Disease: A Conversation with Dr. Andrew Sun

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* Safe sexual practices: Avoid high-risk positions like reverse cowgirl with suboptimal erections, as these can increase injury risk.





On today’s episode of The New Health, Jessica Preston welcomes back Dr. Andrew Sun, a men’s health urologist at Urology Partners of North Texas. In this enlightening discussion, Dr. Sun sheds light on Peyronie’s Disease, an often-misunderstood and under-treated condition affecting up to 10% of men.




Key Takeaways


What Is Peyronie’s Disease?

Definition:
Peyronie’s Disease is a condition characterized by scar tissue (plaque) in the penis, leading to curvature, shortening, narrowing, or other deformities.

Common Symptoms: Lumps or bumps in the penis. Curvature or narrowing during an erection. Pain (especially during erections). Length loss or structural instability (hinge defect). Difficulty or inability to engage in intercourse.

Cause: Often results from microtrauma or wear and tear during intercourse. Associated with softer erections and certain risk factors like diabetes. May have a genetic predisposition, particularly among men of Northern European descent.

The Emotional and Psychological Impact:
Peyronie’s Disease often leads to feelings of shame, depression, anxiety, and even relationship difficulties.

Studies show associations with higher rates of depression, alcoholism, and even suicidal thoughts in men with untreated Peyronie’s.

Supportive, understanding partners can play a significant role in a man’s emotional recovery and treatment journey.




Treatment Options

Medication:
Daily Cialis or Viagra to strengthen erections and prevent further trauma. Anti-inflammatory medications in early stages to reduce plaque formation.

Collagenase Injections (Xiaflex): FDA-approved treatment that dissolves scar tissue. Requires 8 injections over 28 weeks, combined with stretching and modeling exercises. Best for non-calcified plaques.

Traction Devices:
Non-surgical stretching devices help restore length and reduce curvature.

Surgery: Reserved for severe cases or calcified plaques. Options include removing or patching the scar tissue or penile implants to address both curvature and erectile dysfunction.




Key Advice from Dr. Sun

Be proactive:
If you notice changes in your penis (lumps, curves, pain, or shortening), consult a specialist promptly.

Safe sexual practices: Avoid high-risk positions like reverse cowgirl with suboptimal erections, as these can increase injury risk.

Mental health matters: Seek emotional support and consider therapy if Peyronie’s impacts your confidence or relationships.
 
 

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Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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