The Testosterone Link to The Prostate

madman

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On today's episode of the Dr. Geo podcast, we have a special guest, Dr. Mohit Khera, a renowned urologist and professor in the Scott Department of Urology at Baylor College of Medicine. He holds the F. Brantley Scott Chair in Urology and has extensive experience treating male and female sexual dysfunction, men's health, and hormone replacement therapy.

This captivating episode reveals the intricate relationship between testosterone and the prostate. Throughout the episode, we explore the nature of testosterone, its receptors, and its effects on the body. We also address controversies surrounding testosterone and its relationship to the prostate, including the development of prostate cancer. Join us as we gain insights from Dr. Khera's wealth of knowledge on this fascinating topic.
 


 
The Testosterone Link to The Prostate

Mohit Khera

*19:46-22:33 (CAG repeat lengths/AR sensitivity)






*This CAG repeat has different lengths for different people. In humans, the number of AR CAG repeats ranges from as few as 9 to as many as 36, but population averages are typically between 17 and 24 (Chamberlain et al., 1994; Hsiao et al., 1999; Irvine et al., 2000; La Spada et al., 1991). Individuals with higher numbers of AR CAG repeats will normally have diminished testosterone action on cellular functioning, effectively making males with high AR CAG repeats less masculine regarding most sexually dimorphic traits when compared to males with fewer AR CAG repeats (Loehlin et al., 2004; Simanainen et al., 2011)

*
Based on a total sample of 57,826 males occupying 78 countries, the overall average number of AR CAG repeats was found to be 21.40. National averages ranged from 17.00 to 23.16
 

On today's episode of the Dr. Geo podcast, we have a special guest, Dr. Mohit Khera, a renowned urologist and professor in the Scott Department of Urology at Baylor College of Medicine. He holds the F. Brantley Scott Chair in Urology and has extensive experience treating male and female sexual dysfunction, men's health, and hormone replacement therapy.

This captivating episode reveals the intricate relationship between testosterone and the prostate. Throughout the episode, we explore the nature of testosterone, its receptors, and its effects on the body. We also address controversies surrounding testosterone and its relationship to the prostate, including the development of prostate cancer. Join us as we gain insights from Dr. Khera's wealth of knowledge on this fascinating topic.
thanks for posting! great info from Dr. Khara, and a very good reassurance on the benefits of TRT.
 

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This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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