The Enigma of Biotin Interference

madman

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*Biotin supplements can interfere with some LH and FSH assays; therefore, these supplements should be stopped at least 3 days before the blood test depending on how much biotin the patient is taking
 



*Biotin supplements can interfere with some LH and FSH assays; therefore, these supplements should be stopped at least 3 days before the blood test depending on how much biotin the patient is taking
Would you think 100-200mcg biotin to cause an issue in blood tests?
 

 
Would you think 100-200mcg biotin to cause an issue in blood tests?

Sometimes all it takes is looking over the threads to find your answer.

1st thread in post #12 above.


It was laid out in post #2

*While the amount of usual dietary biotin intake is not expected to be high enough to affect these tests, biotin supplementation at doses greater than 1 mg per day can cause either falsely low or falsely high test results, depending on the analyte and platform used for testing.


*some multivitamin/mineral supplements have 1000+ mcg doses

*biotin supplements can easily have well over 1000+ mcg doses (300-10,000 mcg)

*many b-complex supplements can have 1000+ mcg doses
 

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Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

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Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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