madman
Super Moderator
4. Conclusions
The present review details the major two influences on the loss of muscle mass and function with age: muscle fiber atrophy and muscle fiber loss. It is reasonably clear that both of these elements play a role in regulating muscle atrophy and dysfunction at the level of whole muscle/ groups. Nevertheless, few if any research groups focus upon both of these facets simultaneously in humans, nor the prospect of them being interrelated processes (denervation leading to atrophy and/or vice-versa). While this presents experimental challenges, only will investigating these processes simultaneously shed light on the mechanisms of human sarcopenia and dysfunction.
The present review details the major two influences on the loss of muscle mass and function with age: muscle fiber atrophy and muscle fiber loss. It is reasonably clear that both of these elements play a role in regulating muscle atrophy and dysfunction at the level of whole muscle/ groups. Nevertheless, few if any research groups focus upon both of these facets simultaneously in humans, nor the prospect of them being interrelated processes (denervation leading to atrophy and/or vice-versa). While this presents experimental challenges, only will investigating these processes simultaneously shed light on the mechanisms of human sarcopenia and dysfunction.
