madman
Super Moderator
Conclusion:
- laboratories should be aware of the limitations of an automated direct estimate of serum testosterone
- provided that the level is unequivocally in the reference range (>12.5 nmol/L) or unequivocally low (<7 nmol/L), this will probably give an acceptable reflection of gonadal status
- when a borderline result is obtained, (between 7 and 12.5 nmol/L) the factors mentioned above which influence serum testosterone concentration should be borne in mind and in these cases a further, early-morning sample should be analysed for total testosterone, SHBG, LH, FSH and prolactin, along with an estimate of free or bioavailable testosterone
- laboratories should be aware of the limitations of an automated direct estimate of serum testosterone
- provided that the level is unequivocally in the reference range (>12.5 nmol/L) or unequivocally low (<7 nmol/L), this will probably give an acceptable reflection of gonadal status
- when a borderline result is obtained, (between 7 and 12.5 nmol/L) the factors mentioned above which influence serum testosterone concentration should be borne in mind and in these cases a further, early-morning sample should be analysed for total testosterone, SHBG, LH, FSH and prolactin, along with an estimate of free or bioavailable testosterone
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