Are you really sure you require 150 mg/week (MED)? I am getting the sneaking suspicion perhaps a modest dose reduction may be in order....
Don't get me wrong, I love most of your work and have been vocal about it. Just curious if 100 to 125 mg/week may yield some modest NET benefits.
I know I always struggle with dose inflation as well. If we were to plot reward/risk benefit function vs dose for madman is the local max really 150 mg/week?
What's your BP/RHR?