A marker for non-alcoholic fatty liver disease was found to be higher in men with lower testosterone levels, even after controlling for factors of obesity and age. The article says:
"We used the highest sex- specific quartiles of serum total testosterone as references. Suspected non- alcoholic fatty liver disease was diagnosed when serum alanine aminotransferase was >30 IU/L for men and >19 IU/L for women.
"Of the 4758 subjects (49.4% men), the prevalence of suspected non-alcoholic fatty liver disease was inversely correlated with the sex-specific quartiles of testosterone in men and women. In a multivariate model, low total testosterone levels were associated with progressively higher odds of suspected non- alcoholic fatty liver disease in men after adjusting for age, obesity and other metabolic risk factors (P values
for trends <.01)."
"We used the highest sex- specific quartiles of serum total testosterone as references. Suspected non- alcoholic fatty liver disease was diagnosed when serum alanine aminotransferase was >30 IU/L for men and >19 IU/L for women.
"Of the 4758 subjects (49.4% men), the prevalence of suspected non-alcoholic fatty liver disease was inversely correlated with the sex-specific quartiles of testosterone in men and women. In a multivariate model, low total testosterone levels were associated with progressively higher odds of suspected non- alcoholic fatty liver disease in men after adjusting for age, obesity and other metabolic risk factors (P values
for trends <.01)."
