Testosterone Level and Type 2 Diabetes Risk

[Jinzang]

Another meta-analysis finds that higher testosterone levels protects against type 2 diabetes.

Type 2 diabetes is a risk factor for testosterone deficiency and impaired sex steroid status. Some studies also investigated the association of testosterone level with diabetes risk in men, but reported controversial findings. To clarify this issue, we conducted a systematic review and meta-analysis. Thirteen cohort or nested case-control studies with 16,709 participants were included. Meta-analysis showed that higher total testosterone level could significantly decrease the risk of type 2 diabetes in men, and higher free testosterone level could also decrease the risk of type 2 diabetes in men. This meta-analysis suggests that higher testosterone level can significantly decrease the risk of type 2 diabetes in men. Therefore, combined with previous researches, the findings above suggest a reverse-causality scenario in the relation between testosterone deficiency and risk of type 2 diabetes in men.

 

[Nelson Vergel]

Obesity, type 2 diabetes, and testosterone in aging men

Obesity, type 2 diabetes, and testosterone in ageing men (2022) Gary Wittert · Mathis Grossmann Abstract In the absence of obesity, adverse lifestyle behaviours, and use of medication such as opioids serum testosterone concentrations decrease by only a minimal amount at least until very...

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