Testosterone Hysteria: An Interview with Abraham Morgentaler, MD

Nelson Vergel

Founder, ExcelMale.com
Open any paper, browse the Internet or turn on the television and you’ll see the latest scary news on testosterone (T). A new rat study links T to prostate cancer. Several new studies purport to link testosterone replacement therapy (TRT) with a higher risk of having a heart attack or stroke. An advisory committee to the FDA expressed concerns about T overprescribing and fears of heightened risk for a cardiovascular event (CVE), suggesting tighter restrictions. Class action lawyers wasted no time in filing CVE lawsuits for over 300 TRT plaintiffs, and the case is now combined as a multi-district litigation in federal court in Northern Illinois. Like circling sharks, my legal brethren are already trolling for prostate cancer plaintiffs based on the new rat study.
If you’re on TRT, or thinking about it, should you be alarmed? Terrified? I asked Dr. Abraham Morgentaler, the Director of Men’s Health Boston and an Associate Clinical Professor of Urology at Harvard Medical School. He’s “the man” when it comes to T. This guy is probably the world’s foremost expert on men’s sexual and reproductive health and is known for his research and scientific writing on TRT. At a time when T hysteria dominates mainstream discourse, who better to help set the record straight?
Q: Testosterone is under fire these days. Why do you think there’s such a backlash in the medical community against TRT?

Read on
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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