Systemlord
Member
In this episode, Dr. Mohit Khera talks about androgen sensitivity (AR gene CAG repeats), how men at 250 ng/dL can feel perfectly fine and men at 400 ng/dL can feel lousy and have all the signs and symptoms of low-T. Low-T and depression link.
Dr. Mohit Khera ran registry, 100 sites across the country, 850 patients, those patients with low-T, 93% of them have some degree of depression! Those men treated with TRT, only 3% of those patients remained with depressive symptoms.
Dr. Mohit Khera likes to keep estrogen between 30-50 pg/mL. Also, the New England Journal of Medicine, states that estrogen may be the main benefit of TRT, libido, fat loss and strong bones.
Dr. Mohit Khera says that losing 15% of your body weight, you can see a 250 ng/dL increase in Total T.
Dr. Mohit Khera talks about men having problems with erythrocytosis on injections, splitting dosages, switching from IM to SQ, switches men to orals, like Jatenzo and Kyzatex.
Dr. Mohit Khera talks about Natesto, how men respond very well for only an hours worth of peaking of testosterone, binding to receptors, and how activity goes on for hours.
The majority of men treated for hypogonadism, 85% are treated off label for low testosterone due to an unknown cause. Many insurance companies love it because they don’t have to pay for the TRT.
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