Testosterone Deficiency and Treatment – the FACTS

Will Brink

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"Testosterone Deficiency and Treatment – the FACTS" By BrinkZone.com contributor Monica Mollica


Testosterone deficiency and treatment is a very misunderstood and controversial topic among scientists, regulatory agencies (such as the FDA and EMA) and doctors, as well as the popular media.

An international expert consensus conference about testosterone deficiency and its treatment was held in Prague, sponsored by King's College London and the International Society for the Study of the Aging Male (ISSAM). The impetus for this meeting was to address the widespread misinformation and confusion about testosterone deficiency and testosterone therapy

The ultimate goal of this consensus conference was to document what is true or untrue about testosterone deficiency and testosterone therapy, to the best degree possible based on existing scientific and clinical evidence.


There were 18 experts from 11 countries on 4 continents. Specialties included urology, endocrinology, internal medicine, diabetology, and basic science research. Experts were invited on the basis of extensive clinical experience with testosterone deficiency and its treatment and/or research experience.


The final consensus on several key issues related to testosterone therapy was published in the form of 9 resolutions – i.e. facts – coupled with expert comments [2], which I summarize here….


Cont:


http://www.brinkzone.com/anti-aging-and-hrt/testosterone-deficiency-and-treatment-the-facts/
 
Maybe the facts should come from the patients, not the so-called experts.:rolleyes:

The patients are n = 1 subjective and anecdotal, so a balance of symptomology (patient feedback) and the "hard" data is the best balance struck in my view. One can go too far in either direction, either ignoring the science and going on feels alone, or only the science and treating people like a lab number while ignoring how they actually feel. "Experts" have their place. :cool:
 
The patients are n = 1 subjective and anecdotal, so a balance of symptomology (patient feedback) and the "hard" data is the best balance struck in my view. One can go too far in either direction, either ignoring the science and going on feels alone, or only the science and treating people like a lab number while ignoring how they actually feel. "Experts" have their place. :cool:

I agree. I thought the article portrayed a consensus among this group that low T and its associated symptoms should be recognized and addressed as appropriate, because it is beneficial and therapeutic. Thanks for posting.
 
I agree. I thought the article portrayed a consensus among this group that low T and its associated symptoms should be recognized and addressed as appropriate, because it is beneficial and therapeutic. Thanks for posting.

Indeed! It's a good summary by Monica M.
 

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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