madman
Super Moderator
569. Testosterone Breakthrough: A New Testosterone Solution Rocking the HRT World with Shalin Shah - The Thyroid Fixer
<p>What if everything you thought you knew about testosterone therapy was wrong?</p> <p>In this episode, I sit down with Shalin Shah, CEO of Marius Pharmaceutic
Episode Overview
This episode explores the vital role of testosterone in both men and women, busts longstanding myths about hormone therapy, and spotlights a groundbreaking new oral testosterone option, Kyzatrex. Host Dr. Amie Hornaman and guest Shalin Shah (CEO of Marius Pharmaceuticals, makers of Kyzatrex) tackle why testosterone matters, the history and current state of testosterone replacement, common barriers to care, and how their new oral formulation overcomes previous safety and efficacy issues. Listeners get practical clinical insights and tools—whether you're a patient with low T or a clinician wanting to optimize hormone health for your patients.
Timestamps for Major Segments
- 09:07: Why testosterone matters for men & women
- 10:00: Brief history and current state of TRT
- 13:14: Mental health and other benefits of T therapy
- 18:04: Cardiovascular and prostate/cancer risk myths dispelled (TRAVERSE study)
- 20:37: Regulatory barriers and insurance frustrations
- 23:48: Activism: Fighting for testosterone descheduling
- 27:46: The Kyzatrex difference – oral T with no liver toxicity
- 31:39: Reduced estrogen conversion and side effects with Kyzatrex
- 34:17: Impact on fertility and testicular function
- 40:10: Role of SHBG and free testosterone optimization
- 42:12–45:57: TRT for women and the challenges of current options
- 48:03: How to prescribe and access Kyzatrex