Telmisartan for high BP - a caution

hotdog

Member
Four years ago I started taking Telmisartan 40mg for high blood pressure.
Everything I read said it had other benefits...

  • reduces weight gain
  • increases total energy expenditure
  • increases expression of key mitochondrial enzymes in skeletal muscle
  • multiple mechanisms to protect against arterial occlusion
    • including that it increases NO
  • promotes biochemical, biological & metabolic effects - boost athleticism
  • stimulates PPAR-gamma which stimulates the burning of excess calories
    (others ARBs have the property but Telmisartan is >10x better)

Some time after this I began to get painful neuralgias in my back that lasted a few minutes, only sporadic but enough to really annoy. I did not think to connect it back to the Telmisartan.

A year ago we upped the dose to 80mg. A month later I started getting bad diarrhea which would not go away. After 6 months I started getting blood in the stool and a high temperature. A CT scan of my entire abdomen showed diffuse inflammation of the splenic region of the colon and nothing else.
I consulted with my doctor and a functional medicine doctor. Comprehensive stool tests showed no markers that would suggest a serious condition requiring colonoscopy. Previous colonoscopy 5 years ago had no significance.

Finally after 9 months I found "olmesartan induced enteropathy" online. Apparently it can be many months before troubles start. Why I had not put the two together or why the two doctors did not immediately suggest it might be the Telmisartan I don't know. I stopped the drug at New Year and have been absolutely fine since, no neuralgia, no bowel issues. The weight loss during the same 9 month period also resolved the high BP.

I would say if you get any new symptoms, maybe start by testing whether it is the drugs you are on.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Beyond Testosterone Podcast

Online statistics

Members online
4
Guests online
140
Total visitors
144

Latest posts

Back
Top