T. Cypionate steady state

godudi

New Member
Hi All,

Could you please help me to figure out how long does it take testosterone cyp injected daily subcutaneously to reach steady state?

I found on the web that it generally takes between 5 to 6 half-lives for most medication as we build up concentration of a drug, so would it be correct to assume that it takes approximately 40-50 days to reach steady state given t.cyp has a half-life of 8 days?

I need to understand how long I should wait before reevaluting a new dosage and taking blood tests.

Thank you all in advance,
David
 

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Hi All,

Could you please help me to figure out how long does it take testosterone cyp injected daily subcutaneously to reach steady state?

I found on the web that it generally takes between 5 to 6 half-lives for most medication as we build up concentration of a drug, so would it be correct to assume that it takes approximately 40-50 days to reach steady state given t.cyp has a half-life of 8 days?

I need to understand how long I should wait before reevaluting a new dosage and taking blood tests.

Thank you all in advance,
David
This should give you rough idea. If you input 10mg Cyp daily, the 25-30 days mentioned earlier looks about right

 

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Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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