Still Dialing In at 1 Year

Joe, I really like injecting every 3 1/2 days, both HCG and T. It sure makes it simple and I've never used an AI
 
You need to switch doctors to one that uses the correct E2 test and that doesn't over-prescribe Anaztrozole. You very likely need a lot less, like maybe 0.15 mg twice a week, but even that is speculation without the correct E2 test. (the sensitive assay)
 
You are essentially driving self-directing your own protocol since you have a doctor who has failed to provide the proper testing, direction, or support. It's time to examine your options. That should include a new doctor.
 
Daily injections are the best way to have a truly even T level and it should reduce your need for an AI, although you sound like you are extremely sensitive to E2 so you may still need a small dose.
 
I inject 16mg of testosterone daily (adopted July of last year). My total testosterone stays in the mid-900s and my E2 varies between 25 and 28. I have never taken an AI. No issues with hematocrit or hemoglobin. I went to this schedule because my estradiol was climbing and both my doctor and I hoped to avoid Anastrozole. Her (my doctor) one concern when I started this protocol was compliance - would I grow weary of daily injections? Not a problem as I preload my syringes on the weekend for the following week.
 
I switched to a urologist who is infamous on this forum. I wanted to pin at home, have more testing, and have a real doctor paying attention. He put me on 100mg 2x/wk and 1500ui hcg per week. I felt great most of the time. It had its ups and downs. Anastrozole was introduced immediately at 1.5mg/wk. That was too much. I've experimented for 6 months with this protocol. .75mg per week at .25 each dose is perfect until it is not. 1mg dosed through 4 days same thing. Becomes too much. I'm very much in touch with doing this by feel. Unfortunately the doc does a very generic estradiol test.

Why did this doctor immediately start you on 1.5mg/week of Anastrozole? Did you have actual symptoms of high E2? What were they? What was your E2 level on your blood work?

Seems to me that you were feeling better on the lower dosage of Test (150mg/week). Did you have high E2 symptoms then?

I would suggest that you get lab work with a sensitive E2 test on it to find out where you truly are with regard to your Estradiol level.

Finding a new doctor should be on your list of "things to do" also.
 
joe, are you using any Creatine. When testing creatinine levels the summary does not separate creatine and creatinine. Like you stated when breaking down muscle tissue working out, it will also cause an increasing in creatinine levels,.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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