Steroid use and Fertility Outcomes

madman

Super Moderator
33:54-43:25


  • 26:05 Study suggests an association between mobile phone use and reduced sperm concentration in young men.
  • 30:53 Recovery of spermatogenesis after anabolic steroid use is not uniform, highlighting the importance of personalized medical history and counseling.
 
- [00:00](https://youtu.be/ZcvZD3a3ahY?t=0s) The podcast discusses Reproductive Medicine's latest research and introduces topics on PGT platforms and male fertility.

- [06:06](https://youtu.be/ZcvZD3a3ahY?t=366s) A study on non-euploid embryos using PGT platforms reveals varied accuracy in diagnosing aneuploidy and challenges with mosaicism.

- [26:05](https://youtu.be/ZcvZD3a3ahY?t=1565s) Mobile phone use shows an association with lower sperm concentration, impacting male reproductive health.

- [30:53](https://youtu.be/ZcvZD3a3ahY?t=1853s) History of anabolic steroid use may lead to varied recovery rates in male fertility, emphasizing the need for individualized treatment and counseling.

- [43:36](https://youtu.be/ZcvZD3a3ahY?t=2616s) Estradiol levels in frozen embryo transfer cycles affect live birth rates, with a physiological range showing the highest success.

- [48:03](https://youtu.be/ZcvZD3a3ahY?t=2883s) Gender bias exists in letters of recommendation for REI Fellowship applicants, often reflecting deeper systemic issues in academic medicine.

- [01:07:19](https://youtu.be/ZcvZD3a3ahY?t=4039s) ️ The timing and choice of surgery for retained products of conception are debated, with patient-specific considerations important for treatment planning.
 
A 2023 study suggests that men who use their phones more than 20 times a day have lower sperm counts and concentrations than those who use them less frequently:

  • Men who use phones more than 20 times a day: Have a 21% lower sperm concentration and a 22% lower total sperm count (TSC) than those who use them less frequently
  • Men who use phones one to five times a day or less than once a week: Have higher sperm counts and concentrations
The study also suggests that smartphone use may be linked to lower sperm concentration and TSC in young adult males. However, the study doesn't suggest a cause and effect, and it doesn't correlate with a lower likelihood of getting a partner pregnant.

The OVIEW-M is a self-testing device that measures the number and activity of sperm using an optical camera on the front side of an individual's smartphone.
 

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TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Normal range: 300-1000 ng/dL

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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