Steroid Plotter Explanation

Nelson Vergel

Founder, ExcelMale.com
What is SteroidPlotter?
SteroidPlotter is a web-based tool designed to help users plan, visualize, and analyze steroid cycles, including anabolic steroids, testosterone replacement therapy (TRT), and peptides. Its primary function is to plot graphs and calculate estimated blood levels of various compounds based on user-defined dosage, compound selection, injection frequency, and pharmacokinetic properties such as half-life and time to peak concentration[1][2][3].

Key Features
· Cycle Visualization: Users can create visual graphs that show how compound levels fluctuate over time during a cycle. This helps in understanding the pharmacokinetics of different steroids and dosing schedules[2][3].
· Customizable Cycles: Registered users can plan cycles up to 100 weeks long, allowing for detailed long-term planning and adjustments[4][2].
· Extensive Compound Library: The platform supports a wide range of anabolic steroids, hormones, and peptides, with the ability for users to request new compounds if needed[1][2].
· Flexible Dosing Schedules: Users can set various injection frequencies (e.g., daily, weekly, multiple times per week) and compare how these affect blood levels and steady-state concentrations[2][3].
· Comparison Tools: The interface allows side-by-side comparison of different compounds or dosing protocols, making it easier to evaluate the impact of changes in a cycle[1][2].
· Additional Calculators: SteroidPlotter offers tools such as a free and bioavailable testosterone calculator and a testosterone conversion tool for unit conversions[5][6].

How It Works
SteroidPlotter uses pharmacokinetic models to estimate how compounds are absorbed, reach peak concentration, and are eliminated from the body. Unlike simpler plotters, it accounts for the time to peak (Tmax) and does not assume instant release, resulting in more realistic graphs. However, these are still generalized models and do not account for individual variability in metabolism, genetics, or other factors. The results should be considered as estimates, not precise predictions of actual blood levels[1][2][7].

Use Cases
· Planning and optimizing steroid or TRT cycles for smoother blood level profiles.
· Comparing the effects of different esters, dosages, or injection frequencies.
· Visualizing how changes in protocol (such as switching from a short to a long ester) affect steady-state levels and fluctuations.
· Supporting research or personal tracking for those interested in performance enhancement or hormone therapy[2][8][3].

Limitations and Considerations
· The tool provides estimates based on average pharmacokinetics and cannot account for individual differences in metabolism, body composition, or injection technique[1][2].
· It is not a substitute for medical advice and should be used as an educational or planning aid in conjunction with professional guidance.
· The database is updated regularly, often in response to user requests or new scientific data[1][2].

Summary Table: SteroidPlotter at a Glance

Feature

Description

Visualization

Graphs of compound blood levels over time

Customization

Supports various compounds, dosing schedules, and cycle lengths

Comparison

Side-by-side protocol and compound comparison

Calculators

Free/bioavailable testosterone, unit conversions

Pharmacokinetic Modeling

Accounts for half-life, time to peak, and accumulation

Limitations

Estimates only; does not reflect individual variability



SteroidPlotter is widely regarded as a leading online steroid cycle planner, offering a user-friendly interface and advanced features for anyone interested in the pharmacokinetics of anabolic steroids, TRT, or peptide cycles[1][2][3].

1. https://steroidplotter.com/faqs
2. https://www.excelmale.com/threads/steroid-plotter-explanation.31724/
3. https://www.theironden.com/forum/threads/cool-tool.46068/
4. https://www.reddit.com/r/steroids/comments/13de540/psa_new_steroid_plotter_cycle_tracker/
5. https://steroidplotter.com/free-testosterone-calculator
6. https://steroidplotter.com/testosterone-conversion-tool
7. https://www.uk-muscle.co.uk/threads/steroidplotter-updated-dosing-calculator.378893/

8. https://www.anabolicsteroidforums.com/threads/anyone-ever-play-around-with-steroid-plotter.119291/
 
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How accurate are the graphs generated by the steroid plotter?

The accuracy of graphs generated by steroid plotters like SteroidPlotter.com is limited and should be considered approximate rather than precise. There are several factors that affect the accuracy:

## Limitations of the Model

- The plotter uses simplified pharmacokinetic models that do not fully capture the complexity of how steroids behave in the body[1][7].
- It assumes linear absorption and exponential decay based on average half-lives, which may not reflect individual variations[10].
- The model does not account for factors like metabolism differences, body composition, age, and genetic variances[1].

## Individual Variability

- Studies show vastly differing pharmacokinetics among individuals due to factors like metabolism and body composition[1].
- The calculated levels are estimates based on generalized information and cannot account for all individual differences[1].

## Recent Improvements

SteroidPlotter has made efforts to improve accuracy:

- They updated their pharmacokinetic model in 2024 to include more parameters like peak concentration and time to peak where available[7].
- A more advanced model was created for compounds where blood levels don't scale linearly with dosage[7].
- Users can now adjust levels up or down by a percentage to account for individual variation[7].

## Intended Use

The developers emphasize that the tool is meant to provide a rough idea of steroid levels over time, not precise numerical data[10]. It's designed to start conversations about optimizing cycles rather than provide exact blood level predictions[10].

While steroid plotters can be useful for visualizing and comparing different protocols, users should understand the limitations and not rely on them for precise dosing decisions. Consulting with a medical professional and basing treatment on individual symptoms and blood work remains crucial for safe and effective steroid use.

Citations:
[1] FAQs - Steroid Plotter
[3] Modeling Corticosteroid Pharmacokinetics and Pharmacodynamics, Part I: Determination and Prediction of Dexamethasone and Methylprednisolone Tissue Binding in the Rat - PMC
[4] Anyone ever play around with Steroid Plotter?
[5] SteroidPlotter and mg/day
[6] Steroid Plotter Correct? Max Serum Test Release When Time = 0
[7] Changelog - Steroid Plotter
[8] SteroidPlotter Updated (Dosing Calculator)
[9] Pharmacokinetics of testosterone - Wikipedia
[10] Theoretical Steroid Curve Plotter
[12] https://www.eroids.com/forums/general/general-talk/alternative-to-steroid-plot
[13] https://ascpt.onlinelibrary.wiley.com/doi/10.1002/psp4.12287
[14] Diagnosis and Management of Anabolic Androgenic Steroid Use - PMC
[15] The Woolf plot is more reliable than the Scatchard plot in analysing data from hormone receptor assays - PubMed
[17] The Lifetime Prevalence of Anabolic-Androgenic Steroid Use and Dependence in Americans: Current Best Estimates - PMC
[18] https://pharmrev.aspetjournals.org/article/S0031-6997(24)00959-1/fulltext
 
Can I customize the half-lives of each compound in the steroid plotter?

Currently, the steroid plotter does not allow users to customize the half-lives of individual compounds. The half-lives used in the plotter are based on established pharmacokinetic data and studies[11]. However, there have been some recent updates and improvements to the tool that provide more flexibility:

1. In October 2024, a new slider was added that allows users to adjust levels up or down by a specific percentage[5]. This feature is useful if you know you respond differently to a particular compound, as it lets you account for individual variation.

2. The developers have implemented a more advanced pharmacokinetic model for some compounds where blood levels don't scale linearly with dosage[5]. This model includes parameters like peak concentration and time to peak, which can provide more accurate results for certain steroids.

3. The plotter now uses a linear regression equation for some compounds to better mimic the diminishing effect seen as doses increase[5].

While these updates improve the accuracy and flexibility of the tool, they do not allow direct customization of half-lives. The developers seem to prioritize using scientifically established data rather than allowing user-defined values, likely to maintain the tool's reliability and consistency across users.

If you need to account for specific variations or have data suggesting different half-lives, you might consider using the percentage adjustment feature or comparing your results with real-world experiences and blood work.

Citations:
[1] FAQs - Steroid Plotter
[4]
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[5] Changelog - Steroid Plotter
[6] Understanding EQ Half Life
[7] Poll Question 173 – Would character customization have improved Half-Life? | RTSL
[8] Drug Half-Life Calculator
[9] Performance and Image Enhancing Drugs (PIEDs) – hi-ground.org
[10] https://thinksteroids.com/community...e-and-half-life-steroid-half-lifes.134390427/
[11] Cycle planner
[12] Anabolic androgenic steroid abuse in young males - PMC
[13] Assistance with steroid plotter
[14] Switching Compounds Mid Cycle?
[15] https://journals.physiology.org/doi/full/10.1152/physiolgenomics.00226.2010
 

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