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So what's interesting is in this article by Dr. Ramasamy, sex drive was found, among other outcomes such as mood, to be higher when estradiol was above 50 pg/mL. I question why he would prescribe 1 mg anastrozole to patients who have E2 levels at or above 60 pg/mL (when they are experiencing side effects) with these results. [USER=3]@Nelson Vergel[/USER] Do you have any idea?

My use of anastrozole has been increased to a fairly steady at 0.25 mg once per week with my TRT now that I have consistently begun coadministration of HCG (500 units 2-3 times per week). HCG seems to make my estrogenic side effects (head fog, migraine, etc.) much worse than just using testosterone. I am questioning if HCG is actually the reason behind why I experience what I consider to be 'negative E2 side effects'. I can say that my E2 is 20 points higher with HCG use than without, and almost zero increase in TT is seen. 

[URL unfurl="true"]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854098/#ref17[/URL]