Staging Prostate Cancer - MRI, PIRADS, & PSMA | Are Biopsies Still Needed?

madman

Super Moderator

Alex asks medical oncologist Mark Scholz, MD, about the latest imaging and other tests used in the diagnostic and staging process for men who have been recently diagnosed with prostate cancer or men who have had a high PSA, for example, and are investigating further to see if aggressive prostate cancer is present.


0:09 What is the role of 3-Tesla multiparametric MRI in staging prostate cancer?

0:46 What does PI-RADS mean?

3:08 Are both MRI and PSMA PET scan required for staging prostate cancer? In which order should they be done?

3:34 In which order should diagnostic and staging tests and imaging studies be used?
 
Screenshot (16914).webp
 
More great insights from Dr. Scholz. Thanks. Looks like he is in Marina del Rey. Anyone that has seen him and can give us personal viewpoint?
 

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Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

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Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

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The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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