Sperm FNA Mapping: Looking Beyond the Conventional to Find New Hope for Infertile Men

Nelson Vergel

Founder, ExcelMale.com
From Dr Paul Terek

Two decades ago, the field of male infertility held two new truths: That men without sperm in the ejaculate can have sperm in the testicle, and that testicular sperm could be used to create babies with IVF-ICSI. We also learned that testicular sperm tends to be located in “islands” or “pockets” which means that it could be in one place but not another. A veritable hornet’s nest for the reproductive urologist.

One of the first “walls” I faced upon entering the field were patients who came to me after the traditional testis biopsy was unable to find sperm in the testicle, asking “is there anything you could do?” Thinking atmospherically, I invented Sperm Mapping. Indeed, by looking harder and avoiding incisions, we published that Sperm Mapping was both kinder and better at finding sperm than the classic biopsy. And this was good.

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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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