Should You Fast Before a Cholesterol Test?

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Nelson Vergel

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Among the studies that found that fasting may have little impact on cholesterol blood test results was a large 2012 Canadian study of more than 200,000 people that found average levels for HDL and total cholesterol varied less than 2 percent, regardless of whether people had eaten an hour earlier or fasted for 16 hours. LDL cholesterol levels varied by less than 10 percent whether patients had fasted or not, and triglyceride levels varied by less than 20 percent, that study found.

Many European countries no longer recommend that patients fast before a cholesterol test. Nonfasting lipid testing has been standard in Denmark since 2009, and the National Institute for Health and Care Excellence, which develops guidelines in Britain, has endorsed nonfasting lipid testing for the primary prevention of heart disease since 2014. More recently, a joint consensus statement by the European Atherosclerosis Society and European Federation of Clinical Chemistry and Laboratory Medicine reviewed the evidence and agreed that fasting is not routinely required for a lipid profile.

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