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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Should Men on Testosterone Test Their Free Estradiol ?
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<blockquote data-quote="stx359" data-source="post: 131753" data-attributes="member: 19129"><p>In my opinion (for how little that is worth) yes we should only care about free E2. Total E2 is only clinically important after we factor in the effect of SHBG levels. I have come to the conclusion after digesting this site that those of us who have a decently high SHBG are the lucky ones as we can run high total E2 numbers with little concern. I would like to see more people post their free E2 results. I know it costs but I would rather have people do that then go on an AI because they "think" they have high E2 and crash their estrogen. There could easily be an entire forum on here devoted to guys who have disastrous results because of their irrational fear of E2 and (sometimes) unwarranted use of AIs.</p><p></p><p>I once worried that I had an E2 problem but a free E2 test showed me that my numbers are in the normal range. My last labs had a SHBG of 44.5, TT 1008, FT 24.2 and a sensitive E2 of 36.7. Many guys on here have jumped feet first into AI dosing with numbers like that and had disastrous results. My serum free estradiol was 0.8 (Range 0.2-1.5) with a percent of 1.9% (Range 1.7%-5.4%) which is actually on the low end of the range.</p><p></p><p>It is a very informative test. I'd like to see more people post their results if for no other reason than to get more accurate ranges on the test as they are derived from all of the subjects who take it. I think that number might be rather small at this point.</p></blockquote><p></p>
[QUOTE="stx359, post: 131753, member: 19129"] In my opinion (for how little that is worth) yes we should only care about free E2. Total E2 is only clinically important after we factor in the effect of SHBG levels. I have come to the conclusion after digesting this site that those of us who have a decently high SHBG are the lucky ones as we can run high total E2 numbers with little concern. I would like to see more people post their free E2 results. I know it costs but I would rather have people do that then go on an AI because they "think" they have high E2 and crash their estrogen. There could easily be an entire forum on here devoted to guys who have disastrous results because of their irrational fear of E2 and (sometimes) unwarranted use of AIs. I once worried that I had an E2 problem but a free E2 test showed me that my numbers are in the normal range. My last labs had a SHBG of 44.5, TT 1008, FT 24.2 and a sensitive E2 of 36.7. Many guys on here have jumped feet first into AI dosing with numbers like that and had disastrous results. My serum free estradiol was 0.8 (Range 0.2-1.5) with a percent of 1.9% (Range 1.7%-5.4%) which is actually on the low end of the range. It is a very informative test. I'd like to see more people post their results if for no other reason than to get more accurate ranges on the test as they are derived from all of the subjects who take it. I think that number might be rather small at this point. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Should Men on Testosterone Test Their Free Estradiol ?
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