Sexual Dysfunction in Men After a Heart Attack

Nelson Vergel

Founder, ExcelMale.com
OBJECTIVES: The aim of the study is to assess the frequency of sexual dysfunction in men after myocardial infarction (MI).

METHODS: 62 men were asked to fill IIEF 15 to assess sexual dysfunction 3 and 9 months after MI.

RESULTS: Erectile dysfunction (ED), orgasmic dysfunction, decreased sexual desire, decreased intercourse satisfaction, decreased overall satisfaction were recognized respectively by: 61.3%, 24.2%, 62.9%, 71%, 54.8% of men 3 months after MI, and 51.6%, 17.7%, 58.1%, 77.4%, 59.7% of men 9 months after MI. Men with ED had higher serum CRP (C Reactive Protein) (5.8 vs. 3.8; p = 0.04) and creatinine (1 vs. 0.9; p = 0.04) levels in the peri-infarction period and higher serum BNP* (47.4 vs. 24.6; p = 0.04) measured 3 months after MI than men without ED. They had also higher serum testosterone levels than men without ED (12.6 vs. 10.6; p = 0.03). Men with decreased sexual desire had significantly lower serum DHEAs (dehydroepiandrosterone sulfate) levels in the peri-infarction period than men with normal sexual desire (191.1 vs. 224.3; p = 0.044). Men with ED 9 months after MI had higher serum CRP levels in the peri-infarction period (7.5 vs. 4.6; p = 0.0371). Men with orgasmic dysfunction had lower left ventricular ejection fraction (EF) measured in the peri-infarction period (0.4 vs. 0.5; p = 0.0318).

CONCLUSIONS: 1. Men with ED have higher serum CRP and creatinine levels in the peri-infarction period. 2. DHEAs level has an influence on sexual desire and on erectile function after MI. 3. BNP level in post-MI patients affects erectile function. 4. EF has an impact on orgasmic function.

Written by:
Puchalski B, Szymański F, Kowalik R, Filipiak KJ.

Reference: Psychiatr Pol. 2013 Sep-Oct;47(5):811-26.


* Brain natriuretic peptide (BNP), now known as B-type natriuretic peptide or Ventricular Natriuretic Peptide (still BNP), is a 32-amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes).
 

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Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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