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My wife got started on Semaglutide two weeks ago. Her 1st dose was 150mcg. No side effects so the following week she went up to 200mcg. No side effects again. My wife has an uncontrollable appetite she struggles with constantly. The 1st dose cut that oral anxiety substantially. She only was only able to eat one-two small meals during the day. Towards the end of the 7 days it started to wear off. With the 2nd dose of 200mcg, she very rarely feels like eating. Today she had 4 eggs in the morning and has not eaten since then. Seems to be lasting this time. On the 3rd dose she will do 250mcg. So far this is the real deal with people who struggle to lose weight. Increases satiety and decreases hunger.