Same exact dosage, very different results???

[Duece12345]

I have been on the same dosage (60mg e3.5d) for about 9 months. I have had 3 blood test since I started and the first two were pretty close in total test, free test, SHBG, estrogen, etc. However, the last one was much higher. TT went from 543 ->855. Estrogen went from 36->44. The blood was taken at the same time at the same day in week (trough). Exact same needle, dosage, injection spot etc. The doctor asked if I had been taking more! How is this possible??

 

[Cataceous]

Lab error is a possibility, of course. A change of medication potency is another, albeit a less likely one. Rising SHBG can increase total testosterone, and probably total estradiol, but not by this much. Were you fasting? It's not supposed to be necessary for testing these hormones, but there are anecdotes suggesting it helps with test consistency. It's a nuisance, but you could consider a repeat of the lab work.

 

[Vince]

Yeah I agree, my labs vary at times. For me it’s not an issue.

 

[madman]

I have been on the same dosage (60mg e3.5d) for about 9 months. I have had 3 blood test since I started and the first two were pretty close in total test, free test, SHBG, estrogen, etc. However, the last one was much higher. TT went from 543 ->855. Estrogen went from 36->44. The blood was taken at the same time at the same day in week (trough). Exact same needle, dosage, injection spot etc. The doctor asked if I had been taking more! How is this possible??

Something to always keep in mind.

Variance in Peak and Trough T Levels in Men Using Intramuscular T Injections - Excel Male TRT Forum

MP85-14 VARIANCE IN PEAK AND TROUGH TESTOSTERONE LEVELS IN MEN USING INTRAMUSCULAR TESTOSTERONE Bruno Nascimento*, Helen L Bernie, Elizabeth Schofield, John P. Mulhall, New York, NY INTRODUCTION AND OBJECTIVES In men using intramuscular testosterone (IM T), clinical experience shows us that...

www.excelmale.com

 

[Duece12345]

Lab error is a possibility, of course. A change of medication potency is another, albeit a less likely one. Rising SHBG can increase total testosterone, and probably total estradiol, but not by this much. Were you fasting? It's not supposed to be necessary for testing these hormones, but there are anecdotes suggesting it helps with test consistency. It's a nuisance, but you could consider a repeat of the lab work.

not fasting, but similar diet based on time. Yeah I’ll repeat in a few weeks. It just threw me and my doc off.