Review of Studies of Testosterone to Assess Stroke Risk

[Jinzang]

Although two of seven studies showed reduced stroke risk, the review could not come to a definitive conclusion.

Among eight RCTs, a low frequency of stroke events (<5) was observed across both testosterone and control groups, thus precluding any definitive conclusions. Based on these findings, the association between TRT and the risk of stroke in men remains unclear, and further large and methodologically robust studies are needed to establish this relationship.